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  • Intervention Effect of Music Therapy on Patients with Alzheimer's Disease:A Systematic Review and Meta-analysis

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-12-06 Cooperative journals: 《中国全科医学》

    Abstract: Background As a neurodegenerative disease,Alzheimer's disease(AD) has a high incidence rate and rapid development,which seriously affects the quality of life of patients. In recent years,research on music therapy intervention in AD has gradually increased,lacking effective systematic evaluation and analysis. Objective A meta-analysis was conducted on the intervention effects of music in the treatment of cognition,emotion,living ability and sleep disorders in AD patients. Methods A randomized controlled trial was conducted on the intervention effect of music therapy methods on Alzheimer's patients in the Chinese Journal Full Text Database(CNKI),Wanfang Database(Wanfang),VIP Database(VIP),Medline,Elsevier ScienceDirect,PubMed,and Embase by computer search. The search time was from the establishment of each database until February 2023,and the data was analyzed using Review Manager 5.4 software. Results The study included 15 RCT studies with a total of 1 077 patients. The results of meta-analysis showed:The effects of music therapy on cognitive function(MD=4.35,95%CI=1.64 to 7.05,Z=3.15,P=0.002),negative emotion(SMD=-0.71,95%CI=-1.26 to -0.15,Z=2.51,P=0.01),life ability(SMD=-0.91,95%CI=-1.55 to -0.27,Z=2.77,P=0.006) The effect of intervention was better than that of control group. There was no significant difference in sleep disorder intervention between the two groups (MD=-1.04,95%CI=-3.10 to 1.02,Z=0.99,P=0.32). Subgroup analysis showed that The treatment period was <12 weeks (P=0.01),the treatment duration was <45min/ time(P=0.02),the treatment frequency was ≥ 3 times/week(P<0.001),the implementation method was individual(P<0.001),the implementation method was individual + group(P=0.002),and the intervention measure was receiving music therapy(P<0.001) The effect of intervention on cognitive function in the group was better than that in the control group. Treatment period ≥ 12 weeks(P=0.004),treatment frequency <3 times/week(P=0.01),implementation method of individual + group(P=0.02),intervention measure of receiving music therapy(P=0.002),intervention measure of active music therapy(P=0.002),the intervention effect of music intervention group on negative emotions was better than the control group. Conclusion Music therapy can improve the cognitive function,mental state,and daily self activity of Alzheimer's patients. However,due to the low quality of case studies included,more large-scale and high#2;quality evidence-based studies are still needed to verify.

  • 全媒体语境下电视编辑的角色转型与功能拓展

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:在全球文化一体化发展背景下,新媒体正在以其独特的方式对人们的生活形成影响,逐渐地改变着人们日常的生活方式与习惯。在全媒体语境下,电视编辑的职能也发生着变化,竞争节奏也在加快,电视编辑的内涵与外延也在不断扩大,电视编辑应在确定编辑内容的基础上整合资源,利用多方面平台,创新编辑机制,以提供给全媒体更好的编辑内容。本文通过对全媒体语境下电视编辑的角色转型与功能拓展途径研究,浅析电视编辑长久发展的途径。

  • 媒体融合时代电视编导的创作技巧研究

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:随着网络信息技术的进一步发展,我国进入了媒体融合时代。媒体融合时代对于电视编导的创作技巧有着更为严格的要求,编导需要具有着较高的素质和能力,从而能够掌握更多的创作技巧,为电视媒体的发展发挥出自己重要的作用。因此,在竞争力不断加大的同时,电视编导也要能够不断地提高创作技巧,从而能够为广大的电视爱好者提供更多优秀的电视节目和作品,最大化地满足人们的精神需求。本文主要分析了媒体融合时代下电视编导的创作技巧。

  • A Next Generation of Scholarly Communication Ecosystem: Research and Construction——Taking Peking University as an Instance

    Subjects: Library Science,Information Science >> Library Science submitted time 2023-08-27 Cooperative journals: 《图书情报工作》

    Abstract: [Purpose/significance] Based on comprehensive investigation and study worldly, this article provides the research and framework construction of a new scholarly communication ecosystem. The paper provides research and experience of building scholarly communication ecosystem.[Method/process] It generalizes the concept, model, function and development of scholarly communication. Through the analysis of the changes in the scholarly communication environment, the paper points out that the open access, data-driven research paradigm, software tool development, social media, and new changes in education and teaching have driven scholarly communication ecosystem reconstruction. The paper also introduces the research achievements, architecture design, construction experience and service effect of the next generation of scholarly communication ecosystem of Peking University, and sums up the construction experience and effect of institutional repository, research data management, open publishing, scholarly website and research support services.[Result/conclusion] Aiming at openly scholarly communication, the paper proposes a new generation of scholarly communication ecosystem, which provide wholly academic resources and services, covers the entire scholarly life cycle, such as preparation, discovery, analysis, writing, publishing, outreach and assessment. Based on the use of new technologies such as Bibliometrics, deep mining, and so on, the Ecosystem could support for teaching, research, research management and academic assessment. The research helps academic libraries to promote the development of scholarly communication ecosystem and benefits for the improvement of scholarly communication and research innovation.

  • 分析思维降低情感预测影响偏差

    Subjects: Psychology >> Social Psychology submitted time 2023-03-27 Cooperative journals: 《心理学报》

    Abstract: People overestimate the intensity and duration of their affective reactions to events in the future. This is called impact bias (Wilson & Gilbert, 2003). Impact bias influences individuals’ satisfaction with their decision making. Few studies have shed light on how to reduce impact bias in affective forecast based on dual-process theories. According to dual-process theories of human thinking, there are two distinct but interacting systems for information processing. System 1 relies on frugal heuristics and produces intuitive responses, while System 2 relies on deliberative analytical processing. System 2 often overrides the input of System 1 when analytical thinking is activated. Thus, we here hypothesize that analytical thinking reduces the impact bias in affective forecasting.In experiment 1, a total of 240 undergraduates were assigned to play an ultimatum game as proposers and asked to predict how they would feel when their proposals were accepted or rejected by responders. At random, they were told their proposals were accepted or rejected. As soon as they knew the result, they were asked to report how they felt. Before the ultimatum game began, participants were randomly assigned to view pictures of The Thinker to prime analytical thinking or geometric figures as a control condition. The results showed that analytical thinking reduced impact bias in affective forecasting by reducing the intensity of predicted emotions.In experiment 2, a total of 52 undergraduates took part in a memory test. They were asked to predict how they would feel if their score on a memory test exceeded 90% or not before they took the test. As soon as they knew the result that they did not exceed 90%, they were asked to report how they felt. Before taking the memory test, participants were randomly assigned to perform a verbal fluency task with words related to analytical thinking to prime analytical thinking or to a verbal fluency task with words not related to analytical thinking as a control condition. The results showed that analytical thinking reduced impact bias in affective forecasting by reducing the intensity of predicted emotions.In experiment 3, a total of 111 women who had only one child were asked to predict how they would feel if they had a second. Before predicting their feelings, they were randomly assigned to view pictures of The Thinker to prime analytical thinking or geometric figures as a control condition. Results showed that analytical thinking reduced the positive affect of having the second child but not the negative affect of having the second child.In sum, the present research shows that analytical thinking reduces impact bias in affective forecasting by reducing the intensity of predicted emotions. It can help us reduce impact bias in affective forecasting when making decisions and promote satisfaction with those decisions. Limitations and further research are here discussed as well.

  • 基于句法分析及主题分布的关键词抽取模型

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2022-05-10 Cooperative journals: 《计算机应用研究》

    Abstract: Aiming at the problem that TextRank ignores syntactic information and topic information when extracting chapter keywords, propose a chapter keyword extraction model based on syntactic analysis and topic distribution. Model includes two stages of chapter keyword extraction: paragraph and chapter. Firstly, use paragraphs as a unit to extract paragraph keywords by combining word co-occurrence, grammatical and semantic information. Then cluster the paragraphs according to the paragraph topics to form the paragraph topic set. Finally, extract chapter keywords based on the distribution characteristics of paragraph topics. On the open news dataset, the model's extraction effect improves by about 10% compared with the original TextRank. Results show that the method has significantly improved the extraction effect, and prove the importance of grammatical information and topic information.

  • Analytical Thinking Reduces Impact Bias in Affective Forecast

    Subjects: Psychology >> Applied Psychology submitted time 2020-05-07

    Abstract: " People overestimate the intensity and duration of their affective reactions to events in the future. This is called impact bias (Wilson & Gilbert, 2003). Impact bias influences individuals’ satisfaction with their decision making. Few studies have shed light on how to reduce impact bias in affective forecast based on dual-process theories. According to dual-process theories of human thinking, there are two distinct but interacting systems for information processing. System 1 relies on frugal heuristics and produces intuitive responses, while System 2 relies on deliberative analytical processing. System 2 often overrides the input of System 1 when analytical thinking is activated. Thus, we here hypothesize that analytical thinking reduces the impact bias in affective forecasting. In experiment 1, a total of 240 undergraduates were assigned to play an ultimatum game as proposers and asked to predict how they would feel when their proposals were accepted or rejected by responders. At random, they were told their proposals were accepted or rejected. As soon as they knew the result, they were asked to report how they felt. Before the ultimatum game began, participants were randomly assigned to view pictures of The Thinker to prime analytical thinking or geometric figures as a control condition. The results showed that analytical thinking reduced impact bias in affective forecasting by reducing the intensity of predicted emotions. In experiment 2, a total of 52 undergraduates took part in a memory test. They were asked to predict how they would feel if their score on a memory test exceeded 90% or not before they took the test. As soon as they knew the result that they did not exceed 90%, they were asked to report how they felt. Before taking the memory test, participants were randomly assigned to perform a verbal fluency task with words related to analytical thinking to prime analytical thinking or to a verbal fluency task with words not related to analytical thinking as a control condition. The results showed that analytical thinking reduced impact bias in affective forecasting by reducing the intensity of predicted emotions. In experiment 3, a total of 111 women who had only one child were asked to predict how they would feel if they had a second. Before predicting their feelings, they were randomly assigned to view pictures of The Thinker to prime analytical thinking or geometric figures as a control condition. Results showed that analytical thinking reduced the positive affect of having the second child but not the negative affect of having the second child. In sum, the present research shows that analytical thinking reduces impact bias in affective forecasting by reducing the intensity of predicted emotions. It can help us reduce impact bias in affective forecasting when making decisions and promote satisfaction with those decisions. Limitations and further research are here discussed as well.

  • Mid-term epidemical investigation and analysis on the influence of COVID-19 on the psychological status of residents in different regions of China

    Subjects: Psychology >> Medical Psychology Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2020-02-19

    Abstract: Abstract: Objective: To investigate the influence of COVID-19 on the psychological status of residents in different regions of China in the medium term.Methods: Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS),Social Support Rating Scale (Social Support Rate) and disease awareness survey were performed on 3340 residents in different regions in China. Results: The average scores of depression (40.89 ± 10.901) and anxiety (38.35 ± 8.298) were slightly higher than the norm (P <0.05), but had no clinical significance (depression score> 53; anxiety score> 50). Compared with non-Hubei region, no significant difference was found in depression and anxiety scores. Although average score of each group in the SSRS score was> 30,the younger group was smaller than the older group (P <0.05). The disease cognition score was higher in the medical group than in the non-medical group and higher in the younger group (P <0.05). Correlation analysis showed that there was a significant negative correlation between cognition and anxiety or depression scores (P <0.05). Conclusion: Under the leadership of CPC and Chinese Government, the war against epidemic disease of COVID-19 has achieved Partial victory. The anxiety and depression of the general public, especially in Hubei, have been alleviated to some extent, however it is still slightly worse than that in non-epidemic period. The social masses, especially the elderly masses, are still relatively inadequate in understanding the COVID-19, which needs to be further popularized by the community and medical staff. Further popularization of the disease may be an effective way to eliminate anxiety and depression.

  • Willis覆膜支架治疗颈内动脉血泡样动脉瘤的临床效果

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2018-01-25 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To evaluate the safety and short-term efficacy of Willis covered stent for treatment of blood blister-like aneurysms (BBA). Methods Eight patients with BBA were treated with Willis covered stent system during the period from December 2014 to February 2016. The guiding catheter was placed as high as possible to facilitate the delivery of the covered stent system. Results Nine covered stents were implanted in the aneurysms of 8 patients (8 aneurysms), and 8 stents were released successfully in the parent arteries. In 6 patients, angiography immediately after stent release showed complete disappearance of the aneurysm and the parent arteries remained patent. One patient experienced a minor endoleak after stent implantation, and another stent was implanted to eliminate the endoleak. Iatrogeniccarotid-cavernous fistula occurred in 1 patient due to tortuosity of the parent artery, for which superficial temporal artery-to-middle cerebral artery bypass combined with parent artery occlusion was performed instead; the patient recovered smoothly and the bypass remained patent at 6 months after the operation. No other periprocedural complications occurred in these patients. Follow-up study showed no new-onset neurological deficits in these 8 patients, who had mRS score of 0 in 6 patients and of 1 in 2 patients. Digital subtractive angiography at 6 months after the operation demonstrated no aneurysm in these patients, and only one patient showed mild stenosis in the parent artery. Conclusion Willis covered stents are effective for treatment of BBAwith good safety andshort-termoutcomes.

  • S期H1299细胞热损伤后的延迟性DNA双链断裂

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-27 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To study the pattern of DNA double-strand break (DSB) formation in S-phase cells after thermal damage and explore the mechanisms behind heat sensitivity of S-phase cells and delayed DSBs. Methods Flow cytometry was used to analyze the cell cycle arrest in H1299 cells exposed to thermal damage, and EdU incorporation assay was employed to evaluate the DNA replication capacity of the cells. The cells synchronized in S phase were obtained by serum starvation and DSBs were observed dynamically using neutral comet assay. Trypan blue dye exclusion technique was used to analyze the cell viability after thermal damage. Western blotting (WB) was used to detect the phosphorylation of ATM and DNA binding RAD18. Results The percentage of S-phase cells increased significantly after exposure of the cells to 45 ℃ for 1 h (P<0.01). The time-dependent variation pattern of EdU incorporation was similar to that of S-phase cell fraction. The comet tail began to appear only after incubation of the cells at 37 ℃ for some time and the Olive tail moment (OTM) increased with prolonged incubation. Cell death remained low until 7.5 h after heat exposure of the S-phase cells and then increased rapidly. The phosphorylation of ATM first increased but then decreased drastically. In cells with heat exposure, DNA binding RAD18 was attenuated obviously compared that in non-exposed cells. Conclusion Thermal damage causes cell cycle arrest in S phase, and delayed fatal DSBs occur in the arrested cells due to persistent replication and DNA damage repair suppression, which are the possible cause of heat sensitivity of S-phase cells.

  • 尾气膨胀机叶轮用材料耐蚀性能研究

    Subjects: Materials Science >> Materials Science (General) submitted time 2017-03-31 Cooperative journals: 《腐蚀科学与防护技术》

    Abstract:本工作选定尾气膨胀机叶轮常用的FV520B钢、17-4 PH钢和Inco 718合金三种材料为研究对象,通过仿工程工况环境法分别对其在T1、T2及T3下的均匀腐蚀和点蚀行为进行比较研究。结果表明:在T1下,测试腐蚀液浓度范围内,三种材料均表现出良好的耐腐蚀性能,满足工程使用需求。当测试温度为T2时,Inco 718合金在整个腐蚀浓度区间仍表现出优异的耐蚀性,可以满足工程需求;但FV520B钢和17-4PH钢在腐蚀液浓度升高为1.5%时,两者的耐蚀性均发生明显下降;当环境温度进一步升高为T3时,Inco 718合金在整个腐蚀浓度区间仍表现出优异的耐蚀性,但FV520B钢和17-4PH钢的耐腐蚀性能,随混合酸溶液浓度变化,表现出明显的不稳定性,已无法满足工程使用。