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  • 媒介融合时代电视文化节目的创新方向研究——以《上新了·故宫》为例

    Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》

    Abstract:近年来,中国的电视媒体出现了许多具有传统文化特色的节目,其中《上新了·故宫》节目备受关注。节目播出后,其收视率和社会声誉都很显著。这个电视节目不仅拥有独特的文化内涵,而且突出文化情感,赢得了良好的收视率,获得了公众的赞誉,使"故宫热潮"再度被掀起来。处于融媒体时代,传统电视文化节目的制作模式相应地发生了变化,逐渐转向以"运营"为核心的制作方式。从《上新了·故宫》第一季开始,就迅速传播北京故宫的文化内涵。这个电视项目实现了内容和形式上的创新,引起了业界的关注,学术界也对此予以研究。这个电视节目为传统文化节目提供了创新思路,使观众在观看传统文化节目的时候了解故宫文化,促使电视节目在媒体融合时代实现了更好的发展。本论文以《上新了·故宫》为例,着重于研究媒介融合时代电视文化节目的创新方向。

  • Differences in motor cortex synaptic plasticity associated with two forms of exercise in older adults: Evidence from TMS studies

    Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-10-09 Cooperative journals: 《心理学报》

    Abstract: Although studies have found that exercise can lead to changes in the plasticity of the motor cortex, little is known about the changes in primary motor cortex synaptic plasticity associated with different forms of exercise among older adults. The purpose of this study was to compare the differences in motor cortex synaptic plasticity associated with a small hand muscle among older adults who regularly participated in table tennis or tai chi or who were sedentary.Based on inclusion/exclusion criteria and their answers to a self-reported questionnaire, 54 older adults (60~70 years) were selected who often participated in table tennis (n = 18) or tai chi (n = 18) exercise or who were sedentary (n = 18). The target muscle was the abductor pollicis brevis of the right hand. Motor cortex synaptic plasticity associated with the abductor pollicis brevis muscle was induced by a paired combination of peripheral nerve electrical stimulation and transcranial magnetic stimulation with an interval of 25 ms (PAS25). Single-pulse and double-pulse transcranial magnetic stimulation was applied to the left primary motor cortex to measure changes in motor evoked potentials (MEPs) and short-interval intracortical inhibition recorded in the abductor pollicis brevis muscle before and after PAS25, to compare the differences in primary motor cortex synaptic plasticity among the three groups.The results showed that mean MEP amplitudes immediately and 30 and 60 min after PAS25 in the table tennis group were significantly higher than those in sedentary group; mean MEP amplitudes immediately and 30 min after PAS25 in the tai chi group were significantly higher than those in the sedentary group; and mean MEP amplitudes immediately and 30 and 60 min after PAS25 in the table tennis group were significantly higher than those in the tai chi group. There were no differences in the short-interval intracortical inhibition at any time point after PAS25 among the three groups.These results indicated that regular participation in table tennis or tai chi can induce a sustained increase in primary motor cortex excitability in older adults and that there are differences in primary motor cortex synaptic plasticity in older adults associated with different forms of exercise. These results suggest that increased synaptic plasticity in the motor cortex may play an important role in the acquisition and promotion of motor skills during exercise in older adults.

  • Differences in motor cortex synaptic plasticity associated with two forms of exercise in older adults: Evidence from TMS studies

    Subjects: Psychology >> Physiological Psychology submitted time 2023-06-27

    Abstract:     Although studies have found that exercise can lead to changes in the plasticity of the motor cortex, little is known about the changes in primary motor cortex synaptic plasticity associated with different forms of exercise among older adults. The purpose of this study was to compare the differences in motor cortex synaptic plasticity associated with a small hand muscle among older adults who regularly participated in table tennis or tai chi or who were sedentary.
        Based on inclusion/exclusion criteria and their answers to a self-reported questionnaire, 54 older adults (60~70 years) were selected who often participated in table tennis (n=18) or tai chi (n=18) exercise or who were sedentary (n=18). The target muscle was the abductor pollicis brevis of the right hand. Motor cortex synaptic plasticity associated with the abductor pollicis brevis muscle was induced by a paired combination of peripheral nerve electrical stimulation and transcranial magnetic stimulation with an interval of 25 ms (PAS25). Single-pulse and double-pulse transcranial magnetic stimulation was applied to the left primary motor cortex to measure changes in motor evoked potentials (MEPs) and short-interval intracortical inhibition recorded in the abductor pollicis brevis muscle before and after PAS25, to compare the differences in primary motor cortex synaptic plasticity among the three groups.
        The results showed that mean MEP amplitudes immediately and 30 and 60 min after PAS25 in the table tennis group were significantly higher than those in sedentary group; mean MEP amplitudes immediately and 30 min after PAS25 in the tai chi group were significantly higher than those in the sedentary group; and mean MEP amplitudes immediately and 30 and 60 min after PAS25 in the table tennis group were significantly higher than those in the tai chi group. There were no differences in the short-interval intracortical inhibition at any time point after PAS25 among the three groups.
        These results indicated that regular participation in table tennis or tai chi can induce a sustained increase in primary motor cortex excitability in older adults and that there are differences in primary motor cortex synaptic plasticity in older adults associated with different forms of exercise. These results suggest that increased synaptic plasticity in the motor cortex may play an important role in the acquisition and promotion of motor skills during exercise in older adults.
     

  • 基于Frank编码的抗干扰方法

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-07-09 Cooperative journals: 《计算机应用研究》

    Abstract: When the interference enters from the direction of the main-lobe of the radar, adopting the adaptive beamforming algorithm will lead to problems such as beam distortion and migration of the main-lobe. Aiming at the problem of interference entering from the radar main-lobe, this paper proposed an anti-jamming method based on the design of the transmitted waveform. When the signal encoded by Frank is transmitted, the matched filter and the blocking filter are constructed by using the orthogonality of the Frank code, and the received data is passed through the two filters to obtain two signals. Then the interference is suppressed by the adaptive cancellation method, thus the main-lobe interference is suppressed. Finally, simulation results show that the method of waveform design can effectively suppress interference from main-lobe entry.

  • SCMA与极化码的联合检测译码技术

    Subjects: Computer Science >> Integration Theory of Computer Science submitted time 2018-05-24 Cooperative journals: 《计算机应用研究》

    Abstract: This paper combined the SCMA and Polar Codes and proposed a joint SCMA detection and Polar decoding (JDD) scheme for the system. The independent SCMA detection and Polar decoding (IDD) scheme is unable to take full advantage of decoding information which lead to a poor system performance. Aimed at this problem, the proposed JDD scheme can achieve a significant performance gain which iteratively exchanges the soft information between the detector and the decoder by using intrinsic information to update the initial priori probabilities in SCMA detector. Simulation results show that, the performance of the system with JDD scheme has been significantly improved which obtain about 2dB performance gain compared with the IDD scheme.

  • 动态计算模型在组织行为学研究中的应用

    Subjects: Psychology >> Developmental Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》

    Abstract: Computational modeling applies the regulations and rules of mathematics. It can be used to assess the inconsistency of theory and empirical results, integrate and develop theories, and represent complex, nonlinear, and non-recursion organizational behavior phenomena. However, computational models have not been used much in organizational behavior research. Using complex network analysis and a literature review, this study introduced three widely used computational modeling approaches (i.e., agent-based, system dynamics, and cellular automata) and the topics and types of research questions these computational models address. Computational modeling can help researchers to explore new research fields, change the theoretical pattern of organizational behavior, and support and development the existing research achievements. This study is a tutorial manual of computational modeling in organizational behavior research.

  • 职业冲击的新分类及不同理论视角下的影响效应

    Subjects: Psychology >> Social Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》

    Abstract: Uncertainties in the external environment are constant and difficult to predict in a world filled with VUCA (volatility, uncertainty, complexity, ambiguity; Bennett & Lemoine, 2014), which has caused career shocks to become an increasingly important part of current career scholarship. Akkermans et al. (2018) defined a career shock as “a disruptive and extraordinary event that is, at least to some degree, caused by factors outside the focal individual’s control and that triggers a deliberate thought process concerning one’s career” (p. 4). These authors suggested that the occurrence of a career shock can either be positively or negatively valenced (Akkermans et al., 2018); that is, positive career shocks are more likely to be associated with positive career outcomes, and negative shocks are more likely to be associated with negative outcomes. However, due to individual differences in the cognition of events or time factors, this categorization may have some shortcomings. We found that the literature includes several theoretical perspectives that have been or could be used to scaffold our understanding of the positive or negative impacts of career shocks, and a multiperspective model may provide evidence to support the reclassification of career shocks and help clarify the effects of career shocks. First, we found that the main reasons for the positive or negative effects of career shocks on employees’ behaviour can be explained in terms of different mechanisms and processes. More specifically, the transactional model of stress and coping, the job demands-resources model, and affective event theory could help elucidate how different cognitive, motivational and emotional responses to a career shock can influence the effects of such shocks on behavioural outcomes, those providing insights into the different processes by which shocks impact outcomes. Event system theory focuses on the characteristics or attributes of career shock events that make them salient and therefore likely to impact such outcomes, which could also help explain how their impacts can be extended over time as events vary in duration and timing or as event strength evolves. Second, based on the transactional model of stress and coping, the present study proposed a new classification of career shocks, namely, challenging career shocks and hindering career shocks. Third, we explored the mechanism underlying the impacts of challenging and hindering career shocks on individual behaviour based on the transactional model of stress and coping, the job demands-resources model, and affective event theory. We proposed that challenging career shocks are positively related to problem-focused coping, work engagement and positive affectivity and that hindering career shocks are positively related to emotion-focused coping, burnout and negative affectivity. Furthermore, the attributes (e.g., the strength) of events could moderate the effects of career shocks. Finally, we identify a number of avenues for future research, including developing the concept and attributes of career shock, enriching the empirical research on the new classification of career shocks, exploring additional mechanisms underlying career shocks, and examining the outcomes of career shocks. The present study contributes to the emerging career shock literature by providing a new perspective on the classification of career shocks and developing a new dedicated theoretical model to help us understand the mechanisms underlying career shocks and their effects on career processes as well as behavioural outcomes more completely. Our study also has important practical implications for helping employees make sense of and prepare for career shocks; this research can also improve the ability of career counsellors and managers to help employees better cope with career shocks by avoiding their negative impacts, which is conducive to the long-term and stable development of organizations and employees.

  • 职业冲击的新分类及不同理论视角下的影响效应

    submitted time 2023-03-25 Cooperative journals: 《心理科学进展》

    Abstract: Uncertainties in the external environment are constant and difficult to predict in a world filled with VUCA (volatility, uncertainty, complexity, ambiguity; Bennett & Lemoine, 2014), which has caused career shocks to become an increasingly important part of current career scholarship. Akkermans et al. (2018) defined a career shock as “a disruptive and extraordinary event that is, at least to some degree, caused by factors outside the focal individual’s control and that triggers a deliberate thought process concerning one’s career” (p. 4). These authors suggested that the occurrence of a career shock can either be positively or negatively valenced (Akkermans et al., 2018); that is, positive career shocks are more likely to be associated with positive career outcomes, and negative shocks are more likely to be associated with negative outcomes. However, due to individual differences in the cognition of events or time factors, this categorization may have some shortcomings. We found that the literature includes several theoretical perspectives that have been or could be used to scaffold our understanding of the positive or negative impacts of career shocks, and a multiperspective model may provide evidence to support the reclassification of career shocks and help clarify the effects of career shocks. First, we found that the main reasons for the positive or negative effects of career shocks on employees’ behaviour can be explained in terms of different mechanisms and processes. More specifically, the transactional model of stress and coping, the job demands-resources model, and affective event theory could help elucidate how different cognitive, motivational and emotional responses to a career shock can influence the effects of such shocks on behavioural outcomes, those providing insights into the different processes by which shocks impact outcomes. Event system theory focuses on the characteristics or attributes of career shock events that make them salient and therefore likely to impact such outcomes, which could also help explain how their impacts can be extended over time as events vary in duration and timing or as event strength evolves. Second, based on the transactional model of stress and coping, the present study proposed a new classification of career shocks, namely, challenging career shocks and hindering career shocks. Third, we explored the mechanism underlying the impacts of challenging and hindering career shocks on individual behaviour based on the transactional model of stress and coping, the job demands-resources model, and affective event theory. We proposed that challenging career shocks are positively related to problem-focused coping, work engagement and positive affectivity and that hindering career shocks are positively related to emotion-focused coping, burnout and negative affectivity. Furthermore, the attributes (e.g., the strength) of events could moderate the effects of career shocks. Finally, we identify a number of avenues for future research, including developing the concept and attributes of career shock, enriching the empirical research on the new classification of career shocks, exploring additional mechanisms underlying career shocks, and examining the outcomes of career shocks. The present study contributes to the emerging career shock literature by providing a new perspective on the classification of career shocks and developing a new dedicated theoretical model to help us understand the mechanisms underlying career shocks and their effects on career processes as well as behavioural outcomes more completely. Our study also has important practical implications for helping employees make sense of and prepare for career shocks; this research can also improve the ability of career counsellors and managers to help employees better cope with career shocks by avoiding their negative impacts, which is conducive to the long-term and stable development of organizations and employees.

  • A new categorization of career shocks and their effects based on different theoretical explanations

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2022-12-23

    Abstract:

    Most previous studies agree that career shocks can be either positively (receiving an unexpected award) or negatively (unexpectedly losing one’s job) valenced. However, due to individual differences in the cognition of events or time factors, this categorization may have some shortcomings. Based on the transactional model of stress and coping, the present study proposes a new classification of career shocks, namely, challenging and hindering career shocks, and further explores the mechanism underlying the impacts of career shocks on individual behaviour based on the transactional model of stress and coping, the job demands-resources model, affective event theory, and event system theory; finally, the paper clarifies when and why career shocks have positive or negative impacts on employees.

  • 脑出血后血脑屏障损伤机制的研究进展

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《分子影像学杂志》

    Abstract: This paper summarized the main research progress which was relevant to the potential mechanisms of secondaryblood-brain barrier (BBB) dysfunction in adults' intracerebral hemorrhage (ICH). ICH correlated with many causes, illustratingwith examples, cerebral vascular malformations, coagulopathies, high blood pressure and Alzheimer's disease. Remarkableachievement of the cell and molecular signal level has been obtained on the etiologies of BBB dysfunction after ICH.Hemoglobin, thrombin, iron of blood compositions and the inflammatory reaction to them have a big impact on BBBdysfunction after ICH. Knowing the mechanisms underlying the secondary BBB dysfunction after ICH is significant forstudying the pathogenesis of cerebral hemorrhagic stroke.

  • Strategic Positioning of National Natural Science Foundation of China within National Innovation System in New Era

    Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-03-28 Cooperative journals: 《中国科学院院刊》

    Abstract: As the main channel to support basic research, the National Natural Science Foundation of China (refered as science funds hereafter) plays a leading role in the national innovation system. During the 14th Five-Year Plan period, it is urgent to deepen the understanding of the strategic positioning of science funds in the national innovation system to optimize the national innovation system and accelerate the construction of China’s strength in science and technology. This paper reviews the development process of China’s national innovation system and the evolution of funding orientation of science funds, analyzes the characteristics of the national innovation system in the new era, and puts forward the function of science funds in six perspectives, namely, stimulating comprehensive innovation, cultivating innovative talents, connecting efficient system, leading open innovation, shaping scientific culture, and demonstrating deepening reform, and provides decision-making reference for systematically promoting the deepening reform of science funds and better playing the unique role of science funds in the national innovation system.

  • 茶树CsPLK 基因的鉴定与表达分析

    Subjects: Biology >> Botany >> Applied botany submitted time 2019-06-17 Cooperative journals: 《广西植物》

    Abstract:茶树中富含茶氨酸、儿茶素和咖啡碱等重要功能成分,具有较高的价值功效。茶树在生命周期中经常遭受逆境胁迫,VB6 在植物体内参与逆境应答,吡哆醛激酶(PLK,pyridoxal kinase)是维生素B6(VB6)补救途径中的关键酶。为进一步了解PLK在茶树生物合成的功能和作用机理,本研究基于茶树基因组数据库,以龙井43 为材料,采用逆转录PCR(RT-PCR)的方法从茶树中克隆出CsPLK 的基因。该基因序列长为1179bp,编码393 个氨基酸。CsPLK 蛋白和已知物种中PLK 蛋白具有较高的同源性,都是核糖激酶超家族成员。通过构建pET-CsPLK 载体进行原核表达,并鉴定出重组蛋白有很强的催化活性。组织表达特异性分析表明,叶中的表达量比茎、根的高,在根中最低。荧光定量PCR 表示,低温诱导CsPLK 上调表达,干旱诱导CsPLK 下调表达,发现该基因在茶树中有明显的逆境应答,推测CsPLK 在茶树的生长发育、逆境胁迫发挥重要作用。

  • EFFECTS OF Hf ON HIGH TEMPERATURE LOW STRESS RUPTURE PROPERTIES OFA SECOND GENERATION Ni-BASED SINGLE CRYSTAL SUPERALLOY DD11

    Subjects: Materials Science >> Materials Science (General) submitted time 2023-03-19 Cooperative journals: 《金属学报》

    Abstract: The effect of Hf on the as- cast, heat- treated microstructures and stress rupture properties under 1100 ℃ and 140 MPa was investigated in four second generation Ni-based single crystal superalloys DD11 with various levels of Hf (0~0.80%, mass fraction) additions. The results indicate that increasing Hf addition resulted in decreasing the solidus and liquidus temperatures, while it enhanced the volume fraction of (g +g') eutectic and MC carbide as well as solidification segregation. The number of micropores reduced significantly and the volume fraction of residual (g +g') eutectic and MC carbide increased after heat treatment as Hf content increased. Compared to the Hf-free alloy, the stress rupture life was observed to increase in the alloys with 0.40%Hf, but dropped in the alloy containing 0.80%Hf. Hf addition increased the elemental partitioning ratio of Re, Mo, Cr, resulting in increasing g /g' misfit and decreasing the spacing of g /g' interfacial dislocation networks. The solution strengthing effect was also improved with the enhanced concentration of Re, Mo and Cr in g phase in Hf-modified alloys. However, when the Hf content was 0.80% in DD11 alloy, the stress rupture properties was decreased obviously due to high volume fraction of residual (g +g') eutectic and MC carbide in heat-treated microstructures.

  • 不同沼泽湿地土壤碳氮磷生态化学计量学特征及其影响因素

    Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-06-21 Cooperative journals: 《干旱区研究》

    Abstract:干旱区湿地在改善地区生态环境,维护地区生态稳定等方面发挥着重要作用,研究干旱区湿地土壤碳(C)、氮(N)、磷(P)等元素的生态化学计量学特征,有助于深入了解干旱区湿地土壤养分的供给能力及循环与平衡机制。本文以河西走廊西段,疏勒河中下游的草本沼泽(T1)和季节性咸水沼泽(T2)土壤为研究对象,分析了这两种沼泽湿地土壤C、N、P生态化学计量学特征及其影响因素。结果表明:① 0~100 cm土壤C/N、N/P、C/P均为T2(15.07,5.94,98.01)>T1(12.49,2.50,30.22);随土层深度的增加,土壤C/N、N/P、C/P均在T1有两个峰值(0~10 cm和中间层),T2有一个峰值(中间层)。② 0~100 cm土壤C/N、N/P、C/P空间变异性大,且均为T2>T1。③ T1和T2土壤的N/P与土壤水分呈极显著正相关(P<0.01),C/P与土壤水分、全N呈极显著正相关(P<0.01),与碱解N呈显著正相关(P<0.05);T2土壤C/N、N/P、C/P与土壤容重呈极显著正相关(P<0.01),C/N与土壤水分呈极显著的正相关(P<0.01),N/P与土壤有机C呈显著正相关(P<0.05);T1土壤N/P与土壤有机C呈极显著正相关(P<0.01)。④ 土壤水分是影响两种沼泽湿地土壤C、N、P计量比的关键因子。因此,保护干旱区湿地土壤关键在于采取合理的节水用水措施,该结果可为干旱区湿地土壤保护、管理以及生态恢复提供科学依据。

  • 不同沼泽湿地土壤碳氮磷生态化学计量学特征及其影响因素

    Subjects: Environmental Sciences, Resource Sciences >> Basic Disciplines of Environmental Science and Technology submitted time 2020-06-19 Cooperative journals: 《干旱区研究》

    Abstract:干旱区湿地在改善地区生态环境,维护地区生态稳定等方面发挥着重要作用,研究干旱区湿地土壤碳(C)、氮(N)、磷(P)等元素的生态化学计量学特征,有助于深入了解干旱区湿地土壤养分的供给能力及循环与平衡机制。本文以河西走廊西段,疏勒河中下游的草本沼泽(T1)和季节性咸水沼泽(T2)土壤为研究对象,分析了这两种沼泽湿地土壤C、N、P生态化学计量学特征及其影响因素。结果表明:① 0~100 cm土壤C/N、N/P、C/P均为T2(15.07,5.94,98.01)>T1(12.49,2.50,30.22);随土层深度的增加,土壤C/N、N/P、C/P均在T1有两个峰值(0~10 cm和中间层),T2有一个峰值(中间层)。② 0~100 cm土壤C/N、N/P、C/P空间变异性大,且均为T2>T1。③ T1和T2土壤的N/P与土壤水分呈极显著正相关(P<0.01),C/P与土壤水分、全N呈极显著正相关(P<0.01),与碱解N呈显著正相关(P<0.05);T2土壤C/N、N/P、C/P与土壤容重呈极显著正相关(P<0.01),C/N与土壤水分呈极显著的正相关(P<0.01),N/P与土壤有机C呈显著正相关(P<0.05);T1土壤N/P与土壤有机C呈极显著正相关(P<0.01)。④ 土壤水分是影响两种沼泽湿地土壤C、N、P计量比的关键因子。因此,保护干旱区湿地土壤关键在于采取合理的节水用水措施,该结果可为干旱区湿地土壤保护、管理以及生态恢复提供科学依据。

  • 三种干旱指数在干旱区沼泽湿地土壤水分遥感反演中的应用

    Subjects: Biology >> Ecology submitted time 2018-04-14 Cooperative journals: 《生态学报》

    Abstract:湿地水文条件对湿地生态系统结构和功能起着关键作用。借助卫星遥感技术,以干旱区疏勒河中下游沼泽湿地为研究对象,基于Landsat8 OLI遥感影像的温度植被干旱指数(TVDI)、垂直干旱指数(PDI)和归一化干旱监测指数(NPDI)3种干旱监测方法,结合野外湿地实测土壤水分数据进行比较和验证。结果表明:(1)TVDI、PDI和NPDI3种干旱指数在不同土层中均与土壤实测水分呈显著负相关(P TVDI > PDI;(2)研究区同一湿地类型不同土层的土壤水分存在显著差异(P P 草本沼泽 > 季节性咸水沼泽 > 内陆盐沼。

  • 槲皮素对内毒素性心肌损伤的保护作用及机制

    Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》

    Abstract: Objective To evaluate the protective effect of quercetin against lipopolysaccharide (LPS)-induced cardiac injury in mice. Methods C57BL/6J mice were randomized into 4 groups to receive intraperitoneal injection of saline (negative control) or LPS (20 mg/kg), or fed with quercetin (100 mg/kg for 7 days) with or without subsequent LPS injection (quercetin+LPS group and quercetin control group, respectively). Six hour after LPS injection, the mice were tested for cardiac function with an echocardiograph, and the protein expressions of Bax, Bcl-2, iNOS, and eNOS in the myocardium were evaluated with Western blotting; serum NO concentration was also measured. The survival of the mice within 5 days after LPS injection was recorded to draw the survival curve. Results Quercetin pretreatment significantly improved the cardiac function of LPS-challenged mice (P<0.05), and attenuated LPS-induced increment in myocardial iNOS expression and decrement in eNOS level. LPS significantly increased the myocardial Bax expression and slightly decreased Bcl-2 expression; quercetin pretreatment decreased Bax expression to the control level and significantly lowered Bax/Bcl-2 ratio as compared with the LPS group. Serum NO level was significantly increased by nearly 2.5 folds in LPS-challenged mice, but was markedly decreased with quercetin pretreatment (P<0.05). The 5-day survival rate of LPS-treated mice was 10% , which was increased to 45% in quercetin- pretreated mice (P<0.05). Conclusion Quercetin can alleviate LPS-induced cardiac dysfunctions in mice to increase their survival rate following LPS challenge.

  • 左侧背外侧前额叶在程序性运动学习中的作用

    Subjects: Psychology >> Social Psychology submitted time 2023-03-27 Cooperative journals: 《心理学报》

    Abstract: Procedural motor learning includes sequence learning and random learning. Neuroimaging studies have shown that the dorsolateral prefrontal cortex (DLPFC) and primary motor cortex (M1) play significant roles in procedural motor learning; however, the connectivity between the DLPFC and M1 and its relationship with different procedural motor learning are still unclear. In this study, the serial response time task (SRTT) and transcranial magnetic stimulation (TMS) were used to explore the differences in left DLPFC-M1 connectivity between the different types of procedural motor learning. In experiment 1, dual-site paired-pulse TMS was used to detect the optimal interval from the DLPFC to the M1. In experiment 2, the participants were divided into two groups that underwent sequence learning or random learning. Behavioral data, motor evoked potentials from the M1 and electrophysiological data of DLPFC-M1 connectivity were assessed before and after learning. The behavioral results showed that the learning effect of the sequence learning group was better. The electrophysiological results showed that motor evoked potentials from the M1 were the same before and after learning in both groups. At the optimal interval and appropriate stimulation intensity, the DLPFC-M1 connectivity in the sequence learning group was changed, and it was related to learning performance; however that in the random learning group was not significantly changed. The results suggest that enhanced connectivity between the DLPFC and M1 may be an important explanation for the better performance in sequence learning. The results provide robust electrophysiological evidence for the role of DLPFC in motor learning.

  • Functional role of the left dorsolateral prefrontal cortex in procedural motor learning

    Subjects: Psychology >> Physiological Psychology submitted time 2019-12-24

    Abstract: Procedural motor learning includes sequence learning and random learning. Neuroimaging studies have shown that the dorsolateral prefrontal cortex (DLPFC) and primary motor cortex (M1) play significant roles in procedural motor learning; however, the connectivity between the DLPFC and M1 and its relationship with different procedural motor learning are still unclear. In this study, the serial response time task (SRTT) and transcranial magnetic stimulation (TMS) were used to explore the differences in left DLPFC-M1 connectivity between the different types of procedural motor learning. In experiment 1, dual-site paired-pulse TMS was used to detect the optimal interval from the DLPFC to the M1. In experiment 2, the participants were divided into two groups that underwent sequence learning or random learning. Behavioral data, motor evoked potentials from the M1 and electrophysiological data of DLPFC-M1 connectivity were assessed before and after learning. The behavioral results showed that the learning effect of the sequence learning group was better. The electrophysiological results showed that motor evoked potentials from the M1 were the same before and after learning in both groups. At the optimal interval and appropriate stimulation intensity, the DLPFC-M1 connectivity in the sequence learning group was changed, and it was related to learning performance; however that in the random learning group was not significantly changed. The results suggest that enhanced connectivity between the DLPFC and M1 may be an important explanation for the better performance in sequence learning. The results provide robust electrophysiological evidence for the role of DLPFC in motor learning. "

  • 民勤绿洲边缘积沙带形成的环境条件

    Subjects: Geosciences >> Geography submitted time 2019-11-15 Cooperative journals: 《干旱区地理》

    Abstract:甘肃河西地区经过60多年的防沙治沙,在绿洲边缘形成了一条积沙带。民勤绿洲边缘积沙带高4.8~18.6 m,宽30.4~461.4 m。为什么有的地段积沙带高大,而有的地段积沙带相对矮小,或者有的地段积沙带较宽,而有的地段积沙带较窄?对此,以民勤为研究区,通过对民勤绿洲边缘积沙带进行了调查,运用相关分析等方法和SPSS软件进行了分析。结果表明:(1) 民勤绿洲边缘积沙带按形成方式可分为天然灌丛积沙带、乔木林带积沙带、人工固沙林积沙带3种,其中天然灌丛形成的积沙带相对高大,而农田边缘单纯的乔木林带形成的积沙带最窄。(2) 控制积沙带高度的环境因子主要是积沙带与主风向的夹角,即积沙带与主风向的夹角越小,则积沙带的高度越低。上风向对准风沙口时,则积沙带与主风向的夹角越小,积沙带的宽度亦越小。(3) 典型相关分析结果好于单相关分析。结果显示,积沙带的形态主要是由其宽度、宽高比和断面形状决定的,而影响积沙带形态特征的环境因子主要是上风向是否对准风沙口以及沙源的距离,亦即当上风向未对准风沙口时积沙带较宽且断面积较大,积沙带与上风向沙源距离越小则积沙带越高大。