分类: 工程与技术科学 >> 生物医学工程学 提交时间: 2023-05-27
摘要: Digital liquid sample handling is an enabling tool for cutting-edge lifesciences research. Similar to Field Programmable Gate Arrays (FPGA) in Integrated Circuits, we present here an active-matrix thin-film electronicsbased digital microfluidics system, which will be henceforth referred to as Field Programmable Droplets Arrays (FPDA). The system contains 256 256 pixels in an active area of 10.65 cm2, which is capable of manipulating thousands of individually addressable liquid droplets simultaneously. By leveraging a customised TFT-based circuit design solution, it becomes possible to programmatically manipulate droplets at the pixel level. The minimum achievable droplet volume is around 0.5 nl, which is two orders of magnitude smaller than the state-of-the-art reported1. The movement of droplets can be either pre-programmed or controlled in real-time. The FPDA system shows great potential of the ubiquitous thin-film electronics technology in digital liquid handling. These efforts will make it possible to create a true programmable lab-on-a-chip device to enable great advances in life science research.
分类: 心理学 >> 应用心理学 分类: 心理学 >> 心理测量 提交时间: 2023-05-27
摘要: 检验移动阿格纽关系问卷中文版(mARM-C) 的信、效度。采用mARM-C及效标问卷测量574名近期使用过冥想APP的大学生,两周后抽取102名重测。通过探索性因子分析及网络分析发现,该问卷包括5因子共19个条目;验证性因子分析也表明模型拟合良好,且效标关联效度、聚敛效度、区分效度良及内部一致性信度均达到心理测量学标准。因此,mARM-C信效度良好,可用来测量在线自助干预中用户与程序间的数字治疗联盟。
分类: 医学、药学 >> 基础医学 提交时间: 2023-05-27
摘要: 幽门螺杆菌( Helicobacter pylori,Hp)是一种常见的胃肠道感染的革兰阴性杆菌,它主要存在于胃上皮细胞表面和黏液中,与胃溃疡、胃癌和胃黏膜相关淋巴瘤有关。有研究表明幽门螺杆可能诱发或加重某些胃外疾病,近日还有研究报道了幽门螺杆菌与新型冠状病毒肺炎有关;其通过刺激机体产生炎症因子或交叉免疫反应间接或直接的参与疾病的发生和发展。此外幽门螺杆菌还可进入念珠菌内,释放毒素参与胃外疾病并躲避免疫系统和药物作用。本文总结近几年国外对幽门螺杆菌相关胃外疾病的研究报道,旨在引起临床工作者对幽门螺杆菌相关胃外疾病的重视、普及其相关学科知识,避免幽门螺杆菌加重或诱发其他疾病。/t/n【关 键 词】幽门螺杆菌;胃外疾病;交叉免疫反应;新型冠状病毒肺炎