Subjects: Library Science，Information Science >> Library Science submitted time 2023-07-26 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] Analyzing the typical cases and conclusions of OCLC' series reports of the Realities of Research Data Management will provide a reference for the practical development of research data management in China. [Method/process] By case study, network survey and literature review, the paper summarized the main contents and key conclusions of series reports, and analyses the internal relationship of four sub-reports. Furthermore, it summarized the characteristics of the report including the overall view of research data management, the rigor of the research process and the guiding significance of the research conclusions. [Result/conclusion] Four enlightenments are proposed:university research data management service should be suitable for its own development; carrying out various forms of data literacy education activities; strengthening data management service capacity by cooperation; giving full play to the role of academic library.
Subjects: Psychology >> Social Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》
Abstract： The aesthetic objects arouse aesthetic pleasure that is specific and intense. The Pleasure-Interest Aesthetic model (PIA) suggests that aesthetic processing is a dual-process including the automatic process for sensory pleasure and the control process for aesthetic interest pleasure. Here we review recent work on the neural substrates of aesthetic pleasure. A large body of studies demonstrates that the orbitofrontal cortex is automatically activated by the objects of aesthetic appreciation. The orbitofrontal cortex which is responsible for automatic emotion regulation and reward processing of pleasure is generally activated in aesthetic activities and it is the neural basis of the automatic processing for sensory pleasure. Different modes of functional connectivity with the striatum support different aspects of aesthetic processing: the release of endogenous dopamine in the caudate nucleus is concentrated in the early aesthetic stage, and then gradually decreases during the in-depth process of aesthetic experience, while the release of endogenous dopamine in the nucleus accumbens gradually increases during the in-depth phase. This is evidence for the PIA model. However, additional brain circuitry is engaged such that the default mode network (DMN) is activated and the lateral prefrontal cortex is deactivated when the aesthetic flow experience occurs, indicating that beyond the dual-process highlighted by the PIA model there is a higher level of aesthetic flow pleasure. The automatic processing for sensory pleasure and the control processing for aesthetic interest pleasure are different from the aesthetic flow pleasure. Aesthetic flow pleasure is not the satisfaction of the needs of the senses, but the high-level pleasure which is liberated from the spirit; it is the experience of the soul gaining strength and courage and it is related to a clear self-consciousness. Therefore, aesthetic flow pleasure is independent of the automatic processing for sensory pleasure and the control processing for aesthetic interest pleasure. We point out that the PIA model needs to be expanded to include this dimension of aesthetic processing. The extended model includes three levels of aesthetic pleasure including sensory pleasure, aesthetic interest pleasure, and aesthetic flow pleasure. They are generated respectively in three stages of aesthetic appreciation: automatic processing, controlled processing, and integration and sublimation. Further studies should be conducted on how the aesthetic experience could impact upon creativity and to what extent different aesthetic experiences have the same or differential neural bases for giving rise to aesthetic pleasure.
Subjects: Psychology >> Other Disciplines of Psychology submitted time 2021-04-30
Abstract： The aesthetic objects arouse aesthetic pleasure that is specific and intense. The Pleasure-Interest of Aesthetic model (PIA) suggests that aesthetic processing is a dual-process including the automatic processing for sensory pleasure and the control processing for aesthetic interest pleasure. Here we review recent work on the neural substrates of aesthetic pleasure. A large body of studies demonstrate that the orbitofrontal cortex is automatically activated by aesthetic objects and different modes of connection with the striatum support different aspects of aesthetic processing. These results consistent with the PIA model. However, the default mode network (DMN) is activated and the lateral prefrontal cortex is deactivated when the aesthetic flow experience occurs, indicating that beyond the dual-process highlighted by the PIA model there is a higher level of aesthetic flow pleasure. We point out that the PIA model needs to be expanded to include this dimension of aesthetic processing and further studies should be conducted on how the aesthetic experience could impact upon creativity and to what extent different aesthetic experiences have the same or differential neural bases for giving rise to aesthetic pleasure.
Peer Review Status:
Awaiting Review
Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-05-15 Cooperative journals: 《中国全科医学》
Abstract： The increasing prevalence of chronic diseases globally poses major challenges to the health of societies and individuals. Managing chronic diseases requires long-term treatment and monitoring，placing demands on patients' lifestyles. With the aging of the population and changes in lifestyle，chronic disease prevention and control are becoming more and more important. In recent years，as scientific and technological innovation in the field of healthcare develops in depth，and the application of artificial intelligence in healthcare has gradually become one of the important strategic directions of the country，the traditional method of chronic disease management relies too much on the offline communication between the doctor and the patient， which leads to the doctor not being able to maintain long-term and effective communication and follow up with the patient，and the patient may not be able to be detected and monitored by the doctor in a timely manner when his or her condition changes. In addition，the traditional chronic disease management approach is usually a generalized approach that fails to adequately consider the individual differences of each patient. Given the limitations of traditional chronic disease management methods，this study aims to provide more convenient and efficient primary care services using intelligent robots. Through personalized health management plans，assisted medical diagnosis，and timed medication reminders，the intelligent robot is committed to improving patients' quality of life，reducing the pressure on healthcare resources，and promoting the development of intelligent healthcare management globally.
Subjects: Materials Science >> Materials Science (General) submitted time 2023-03-31 Cooperative journals: 《腐蚀科学与防护技术》
Abstract： The corrosion behavior of different locations of X65 steel oil pipeline was investigated using a high-temperature corrosion test chamber, which aims to simulate the real corrosive environments of oil pipelines. Then the morphology and composition of the corrosion scales were characterized by Scanning Electron Microscope (SEM), Energy Dispersive Spectrometer (EDS) and Xray diffraction (XRD). The results demonstrated that with the increasing time, the corrosion rate of X65 steel increased firstly and then slowed down to a lower level for long term. While temperature has obvious influence on the corrosion rate of the X65 steel, which presented the top area of the pipeline, where the steel suffered from uniform corrosion with formation of water drop-like corrosion products adhere to the steel surface. At low temperature, the main component of the corrosion products were iron oxide, in the contrast, at high temperature a protective corrosion product composed mainly of Fe2S could form.
Subjects: Biology >> Bioengineering submitted time 2017-07-24 Cooperative journals: 《中国生物工程杂志》
Abstract：摘要：目的 建立性激素结合球蛋白（SHBG）基因条件敲除小鼠模型，为探讨胎盘组织中SHBG在体内的生理功能及其与妊娠期糖尿病发病关系提供实验手段。方法 首先运用生物信息学手段确定小鼠SHBG基因组序列，构建SHBG打靶载体，以电穿孔方法将其导入小鼠ES细胞，筛选培养阳性ES细胞并行PCR鉴定，并将正确同源重组的ES细胞注射进小鼠囊胚，移入受体小鼠子宫；将获得的嵌合体小鼠与C57BL/6J小鼠交配，筛选后获得Flox小鼠，该小鼠与EIIa-Cre转基因小鼠杂交，子代多次自交获得SHBG全身基因敲除(SHBG-/-)的小鼠。 结果 运用同源重组及ES细胞技术建立了SHBG基因的Flox小鼠，并利用Cre/Loxp重组酶系统建立了SHBG基因全身敲除小鼠模型，PCR方法从基因水平证明了SHBG基因Flox小鼠及SHBG基因全身敲除小鼠模型建立成功。对基因敲除鼠进行初步表型分析发现：SHBG基因全身敲除小鼠的生长发育与野生型小鼠相比无明显肉眼所见异常，SHBG基因全身敲除雌雄小鼠均具有生殖能力。结论 成功建立SHBG基因全身敲除小鼠模型，通过对基因敲除鼠进行初步表型分析，发现SHBG基因全身敲除小鼠外观上发育正常，为进一步研究SHBG在妊娠期糖尿病中的作用奠定了基础。
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