Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2023-10-24 Cooperative journals: 《中国全科医学》
Abstract： Background The disorder of serum uric acid metabolism during pregnancy is associated with adverse pregnancy outcomes，while few studies have analyzed and compared the correlation of serum uric acid and uric acid/creatinine ratio levels with adverse pregnancy outcomes. Objective To explore the correlation of serum uric acid and uric acid/creatinine ratio levels with adverse pregnancy outcomes in late pregnancy. Methods Based on the occurrence of adverse pregnancy outcomes，the data of pregnant women with singleton live births who were routinely examined and delivered at Nanjing Drum Tower Hospital from 2015 to 2022 at a ratio of 1:1 were collected. Ultimately，a total of 743 pregnant women were collected， including 344 in the normal group and 399 in the adverse outcomes group. Serum uric acid and serum uric acid/creatinine ratio were divided into three levels by quartiles，respectively， including Q1（serum uric acid ≤ 257 μmol/L），Q2（serum uric acid 257-359 μmol/L），Q3（serum uric acid ≥ 359 μmol/L）and q1（serum uric acid/creatinine ratio ≤ 5.88），q2 （serum uric acid/creatinine ratio 5.88-7.94），q3（serum uric acid/creatinine ratio ≥ 7.94）. According to the median age of pregnant women，they were divided into the age group<30 years old（341 cases）and age group ≥ 30 years old（402 cases）. Based on previous pregnancies and deliveries，they were divided into the primiparous group（539 cases）and multiparous group （194 cases）. The correlation of serum uric acid and serum uric acid/creatinine ratio levels with adverse pregnancy outcomes was analyzed by using multivariate Logistic regression. Results Pregnant women in adverse outcomes group were older with higher levels of BMI，serum uric acid，serum uric acid/creatinine ratio and triglycerides than those in the normal group（P<0.05）. After adjustment for confounders，the multivariate Logistic regression results of the effect of serum uric acid and serum uric acid/ creatinine ratio on adverse pregnancy outcomes showed that， compared to Q1 serum uric acid level，the risk of preeclampsia （AOR=4.41，95%CI=2.16-8.99）and intrauterine growth restriction（AOR=3.59，95%CI=1.08-11.96）increased at Q3 serum uric acid level（P<0.05）；compared to q1 serum uric acid/creatinine ratio level，the risk of preeclampsia（AOR=2.33， 95%CI=1.13-4.79；AOR=3.56，95%CI=1.68-7.56） increased at q2 and q3 serum uric acid/creatinine ratio levels. Compared to q1 serum uric acid/creatinine ratio level，the risk of preterm labor（AOR=2.76，95%CI=1.33-5.71）and intrauterine growth restriction（AOR=5.15，95%CI=1.39-19.14）increased， while the risk of macrosomia（AOR=0.43，95%CI=0.19-0.98） and large for gestational age（AOR=0.38，95%CI=0.15-0.96）decreased（P<0.05）. The results of the effect of serum uric acid and serum uric acid/creatinine ratio on preeclampsia and preterm labor in different age groups showed that， compared to Q1 serum uric acid level，the risk of preeclampsia increased in both age groups at Q3 serum uric acid level（P<0.05）；compared to q1 serum uric acid/creatinine ratio level，the risk of preeclampsia increased among women aged ≥ 30 years at q2 and q3 serum uric acid/creatinine ratio level（P<0.05）. The results of the effect of serum uric acid and serum uric acid/creatinine ratio on preeclampsia and preterm labor in different pregnancies and deliveries groups showed that compared to Q1 serum uric acid level，the risk of preeclampsia increased at Q3 serum uric acid level among primiparous women（P<0.05）；compared to q1 serum uric acid/creatinine ratio level，the risk of preeclampsia increased at q2 and q3 serum uric acid/creatinine ratio level among primiparous women， as well as the risk of preterm birth at q3 serum uric acid/creatinine ratio level among primiparous women （P<0.05）. Conclusion Elevated levels of serum uric acid and serum uric acid/creatinine ratio were associated with the risk of preeclampsia and intrauterine growth restriction，in which preeclampsia mainly occurred in pregnant women aged ≥ 30 years or primiparous women. The risk of preterm labor was increased at high levels of serum uric acid/creatinine ratio， primarily in primiparous women. Serum uric acid/creatinine ratio predicted more adverse pregnancy outcomes than serum uric acid.
Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-10-09 Cooperative journals: 《心理科学进展》
Abstract： The natural speech rate is from two to six syllables per second. Listeners can understand speech accelerated up to three times. That is, the temporal bottleneck of speech is 8~12 syllables per second. This temporal bottleneck closely aligns with the alpha band of neural oscillations. Moreover, alpha oscillation may dictate the temporal resolution of perception. The faster alpha oscillation, that is, the shorter alpha cycle, leads to a shorter threshold of the fusion of two stimuli. Thus, the current study investigates whether and how accelerated speech comprehension depends on the speed of alpha oscillation. Firstly, we aim to ascertain whether the temporal bottleneck of accelerated speech comprehension is consistent with the speed of alpha oscillation. This relationship will be investigated both between and within subjects. In the between-subject experiment, we will test whether individuals with faster alpha oscillations show a shorter threshold in accelerated speech comprehension. In the within-subject experiment, we will examine the consistency between prestimulus alpha speed and speech comprehension in each trial. We'd like to find that, while listeners have a faster alpha oscillation, they comprehension of accelerated speech is better. Secondly, we will investigate how the speed of alpha oscillation modulates accelerated speech comprehension. To be specific, we will manipulate alpha oscillation at a slower (8 Hz) or faster (12 Hz) speed, and then observe the following speech comprehension performance at a syllable rate of 10 Hz. Especially, we aim to find whether this influence occurs at a higher processing beyond the sensory level. Therefore, we design two experiments to manipulate the speed of alpha oscillation. In one experiment, we will use pure tones with different amplitude modulations to induce different alpha oscillations. In the other experiment, we will use transcranial alternating current stimulation (tACS) to modulate oscillatory activity. To investigate the alpha band impact on higher-level processing, we will place electrodes of tACS not only in the temporal cortex but also in the frontal cortex. We'd like to find that: 1) The speech comprehension will be better under the faster (12 Hz) alpha oscillation than under the slower (8 Hz) alpha oscillation; 2) This influence will be detected under alpha modulations in both temporal and frontal cortex. Finally, we will explore how the speed of alpha oscillation affects the neural representation of speech. The neural representation of speech will be analyzed by the temporal response function (TRF), which shows how speech envelope is encoded in neural response. We will analyze how the speed of alpha oscillation modulates the TRF, and how this neural modulation will predict the behavioural performance of speech comprehension. We'd like to find the underlying neural mechanism of how alpha oscillation affects the neural processing of speech comprehension.In sum, we propose a hypothesis to explain how alpha oscillations influence the bottleneck of accelerated speech comprehension. It is hard to process two or more stimuli simultaneously within one cycle of alpha oscillation. Therefore, when the speech rate is slower than the speed of alpha oscillations, one syllable lasts across multiple alpha cycles, allowing for speech to be fully processed and recognized. However, as speech speed gradually increases beyond the frequency of alpha oscillations, multiple syllables exist within one alpha oscillation cycle, leading to competition for cognitive resources and incomplete processing, resulting in difficulty with speech comprehension. Together, we will utilize accelerated speech to investigate the modulation of alpha oscillations on the temporal bottleneck of comprehension. We'd like to find whether alpha oscillation is attributed to higher cognitive processes and explored how alpha oscillation manifests in neural representations of stimuli. We aim to gain a better understanding of how neural oscillations regulate the temporal resolution of perception and to further investigate the general mechanisms underlying the impact of neural oscillations on rapid temporal processing.
Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》
Abstract：本文结合响水广播电视台新建成的广播移动直播车的设计概况,对移动直播车系统从设计原则、车体布局、系统主要设备选型等几个方面作出详细的总结介绍。
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc. submitted time 2023-08-31 Cooperative journals: 《中国全科医学》
Abstract：背景 抗生素滥用导致的耐药问题已成全球重大公共卫生议题，减少公众上呼吸道感染的抗生素不合理使用是我国治理抗生素滥用的重要策略，识别上呼吸道感染疾病病症特点及其对抗生素不合理使用行为的影响有助于临床医生设计更为精准的干预政策。目的 定量分析公众上呼吸道感染症状的潜在模式，探究其对抗生素使用行为的影响。方法 本研究采用整群随机抽样调查，于 2022-07-2008-02 选取重庆市三个县（区）的公众作为调查对象。调查公众上呼吸道感染疾病症状、公众上呼吸道感染抗生素使用行为、公众抗生素使用知识及人口学特征。采用潜在类别分析方法鉴别公众上呼吸道感染疾病症状的潜在模式，采用多因素 Logistic 回归分析探索不同潜在症状模式对抗生素使用行为的影响。结果 815 位公众参与本研究。其中，30.06%（245/815）受访者存在无处方从药店购买抗生素，14.72%（120/815）受访者使用过抗生素自我药疗以应对上呼吸道感染。公众抗生素合理使用知识水平较低〔（2.31.7）分〕。上呼吸道感染疾病发病模式方面，潜在类别分析共识别 4 种症状模式，包括多样症状组 39 例（11.41%）、全身症状组 124 例（15.21%）、鼻咽症状组 282 例（34.60%）和轻微症状组 316 例（38.77%）。多因素 Logistic 回归分析显示：相较于轻微症状组，鼻咽症状组出现无处方购买抗生素行为的概率更高（OR=1.538，P<0.05），结果在调整知识与人口学变量后仍显著。除个体疾病症状潜在模式外，年龄和医保类型也对公众无处方抗生素购药行为有显著影响（P<0.05）。抗生素使用知识水平对抗生素自我药疗行为有显著影响（OR=0.869，P<0.05），对公众无处方抗生素购药行为也有显著影响（OR=1.155，P<0.05）。结论 公众上呼吸道感染症状存在 4 种潜在模式，疾病病症模式显著影响公众抗生素的合理使用，应着重关注出现鼻咽症状患者的抗生素不合理使用行为。
Subjects: Library Science，Information Science >> Library Science submitted time 2023-08-26 Cooperative journals: 《图书情报工作》
Abstract： [Purpose/significance] Automatic identification and extraction of research design fingerprint from scientific papers is able to provide researchers with significant methodology and research support for project design, validity evaluation of research methods, problem diagnosis of research process and identification and evaluation of research results.[Method/process]The paper, based on the concept model of research design fingerprint in scientific papers, proposes amulti-rule hybrid machine learning methods to design and implement the fingerprint identification algorithm model and analyze and verify the feasibility and validity of the methodby sample data in the field of datamining.[Result/conclusion] The results show that in addition to the research data and research trends, the recognition accuracy of other research design fingerprint is almost 80%. And the acceptance of coverage, in addition to research tools and research data, is almost 80%.
Subjects: Library Science，Information Science >> Information Processing submitted time 2023-08-14
Abstract： Digital transformation of enterprises requires the whole-life cycle management of data. Data identification and archiving is an important means to solve the problem of traditional unstructured documents that are difficult to be directly processed by big data technology. Based on enterprise data governance, master data management is introduced into data archiving, and enterprise data is divided into three categories: master data, transaction data, and analytical data. Using macro identification method to identify these three types of data. Determining the scope of data archiving, and include metadata such as ER diagrams, data dictionaries, and data lineage diagrams into the scope of metadata archiving, integrating archived data into the construction of enterprise data lake as the best path for data archiving. The archives department can accelerate integration into the national big data strategy by implementing a "dual system" of electronic file and data archiving, piloting data archiving in large state-owned enterprises, and actively participating in data governance to enhance the data literacy of the archives work team.
Peer Review Status:
Awaiting Review
Subjects: Geosciences >> Geography submitted time 2020-06-02 Cooperative journals: 《干旱区地理》
Abstract： 准确评价地下水对河水的补给量是流域水资源量管理和合理利用的基础。在马莲河流域下游采集不同季节地表水和地下水样品7s组，利用Cl-、电导率(EC)和D80同位素多方法联合评价，识别了地下水补给河水的位置、补给量及其季节变化。结果表明:马莲河水EC和C1一质量浓度沿着流向均呈降低趋势，8D和8'80值沿流向减小。雨季EC和C1一质量浓度最低，8D和8'8 0值最高。地下水各组分浓度均低于河水，时空变化不明显。地下水单宽排泄量存在时空变异，上段和下段为地下水强排泄区，中段地下水排泄较弱，不同季节地下水排泄量占总排泄量的72. 20%9s.07%。雨季地下水单宽排泄量显著降低，河水中基流比例由雨季前期的68. 89%降至29.43% ,整体上，地下水补给河水季节变化明显，而空间变化规律较为稳定。研究成果有利于深入认识河水和地下水的相互作用机制，并为当地水资源利用提供基础依据。
Subjects: Library Science，Information Science >> Philology submitted time 2016-03-10
Abstract：提出用于描述科技文献核心知识的“研究设计指纹”概念，综合研究分析了相关的科技文献规范描述框架，创建“基于科技文献的研究设计指纹描述框架”，以增强科技文献的机器计算可执行性、知识粒度性、知识关联性、结构的扩展性以及研究设计思路的可视性，为科研人员快速发现研究设计方法、研究设计工具等指纹提供了新的思路与方法。
Peer Review Status:Awaiting Review
Hits
Hits
Downloads
Comment
YES