Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2024-06-17
Abstract: OBJECTIVE: Medicinal herbs and decoction pieces in the 2020 edition of Chinese Pharmacopoeia (Part 1) includes a total of 616 items of traditional Chinese medicine. This study is aimed to grasp the overview of all traditional Chinese medicine and discover special ones. METHODS:This study conducted statistical analysis of their basic information such as the properties, dosage and usage. RESULTS:The Chinese Pharmacopoeia has 9 descriptions of the four properties, with the highest number of warm medicines. For the five tastes, the number of bitter medicines is the highest. For meridian tropism, the liver-channel medicines are the majority. Huanglian with 6 meridians is the Chinese medicine with the most meridian tropism. For toxicity, a total of 83 traditional Chinese medicines has clear toxicity descriptions, divided into three levels: with high toxicity , toxic , and with low toxicity . For efficacy, the heat clearing effect is the majority. Hongqi and Huangqi are the medicines with the most efficacy. For application, the frequency of swelling and pain is the highest. Huanglian is the medicine with the most applications. For the usage, 369 medicines are all taken orally by decoction, while others used externally, taken in pill or powder, swallowed in powder or after mixing with water. For the dosage, the average is 6-13g. The minimum value is 0.015g of Chansu and the maximum one is 120g of Maozhaocao. For attention and storage, 97 medicines have pregnancy contraindications; Almost all medicines need to be stored in a dry place. CONCLUSION:There are some issues in the 2020 edition of Chinese Pharmacopoeia (Part 1), such as a few items with indistinct properties of TCM, writing standardization that need improvement, and some unclear information. It is hoped to enlighten the revision of next Chinese Pharmacopoeia.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2024-06-14
Abstract: OBJECTIVE:Test and evaluate the teaching ability of generative artificial intelligence ChatGPT in Traditional Chinese Medicine majors in higher education. METHODS:Using teacher ethics, professional knowledge and teaching ability, teaching design ability, heuristic teaching ability, personalized teaching ability, error correction ability, teaching evaluation ability, and impartiality as evaluation indicators, 1940 Q&A sessions are conducted with ChatGPT and then calculate the accuracy and similarity of ChatGPT’s output answers. RESULTS:Generative artificial intelligence ChatGPT has shown excellent teacher ethics and good personalized teaching ability. However, it does not yet possess the ability to teach traditional Chinese medicine professional knowledge. The teaching design ability, error correction ability, teaching evaluation ability, heuristic teaching ability, and fairness in the field of traditional Chinese medicine are all relatively poor. CONCLUSION:Generative artificial intelligence ChatGPT is still lack of teaching ability in traditional Chinese medicine majors in higher education, and we should be vigilant against fairness and misinformation.
Peer Review Status:Awaiting Review
Subjects: Nursing >> Nursing Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2024-06-05
Abstract: A case of giant cell infection secondary to intracranial venous sinus thrombosis was summarized and analyzed. In this case, headache was the main clinical manifestation, accompanied by vomiting and cold sweat, without fever or cough. After admission, relevant examinations were improved, treatment such as reducing intracranial pressure, anticoagulation and antiviral were provided, lumbar puncture and intracranial angiography were improved, vital signs of patients were closely monitored, the formation of cerebral hernia was prevented by basic nursing such as decubitus position, diet and urine and bowel movements, medication and postoperative signs were monitored, and various treatments and nursing were conducted to promote the recovery of patients.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2024-05-17 Cooperative journals: 《中国全科医学》
Abstract: Background Establishing the advantageous diseases in the field of traditional Chinese orthopedics treated with manual therapy will promote the development of manual techniques and dominant discipline. However,the current evaluation and selection lack a quantitative evaluation process based on evidence-based medicine. Objective To systematically review systematic reviews of diseases in the field of traditional Chinese orthopedics treated with manual therapy using evidence mapping methodology and explore the advantageous diseases in this field. Methods Computerized searches were conducted in PubMed, EMbase,The Cochrane Library,Web of Science,SinoMed,China National Knowledge Infrastructure,Wanfang Data,and VIP database to collect systematic reviews of diseases in the field of traditional Chinese orthopedics treated with manual therapy from inception to March 5,2023. The evidence distribution characteristics were presented using a combination of charts and text. Results A total of 126 systematic reviews published from 2003 to 2023 were included,showing an overall increasing trend in the quantity of relevant studies both domestically and internationally. Methodological quality assessment results indicated that 13 reviews were of moderate quality,64 were of low quality,and 49 were of very low quality. The evidence map showed that the research evidence in the field of traditional Chinese orthopedics treated with manual therapy mainly focused on 18 clinical diseases,including cervical spondylosis,low back pain,knee osteoarthritis,lumbar disc herniation,ankle sprain,adhesive capsulitis of the shoulder,cervicogenic headache,atlantoaxial subluxation,distal radius fracture,lateral epicondylitis of the humerus,carpal tunnel syndrome,lumbar sprain,scoliosis,hip osteoarthritis,fibromyalgia syndrome,myofascial pain syndrome,rotator cuff injury,and supracondylar fracture of the humerus,demonstrating beneficial or potentially beneficial effects. Conclusion Manual therapy is widely used in the clinical practice of traditional Chinese orthopedics. However,due to methodological shortcomings and a lack of research evidence on safety and cost-effectiveness,future efforts should focus on multi-level inter-agency cooperation to establish sound evaluation standards and systems,improve research quality,update research evidence,and further explore the advantages of manual therapy in the field of traditional Chinese orthopedics.
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2024-02-26
Abstract: Objective. To study the main differential metabolites of Xihuang Pill (XHP) in rat serum and the mechanism of related pathways of metabolites on breast cancer. Method. Qualitative and quantitative analysis of metabolites in XHP drug serum group and blank serum group by liquid chromatography-mass spectrometry (LC-MS) technology. And using sample correlation heat map and multivariate statistical analysis methods to compare the metabolic differences between the two groups. The metabolites were analyzed by cluster analysis, Variable Importance in Projection (VIP) analysis, Kyoto Encyclopedia of genes and Genomes (KEGG) compound classification and KEGG functional and enrichment topology analysis. Result. LC-MS technology identified a total of 765 metabolites in the XHP drug serum group; a total of 697 metabolites in the blank serum group. VIP analysis screened the top 30 serum differential metabolites that were significantly different between the two groups, such as Abscisic acid, Quillaic acid, 2,2-Bis(4-hydroxyphenyl)-1-propanol, Corey PG-Lactone Diol, (S)-Naproxen and so on. KEGG compound classification showed that most of the metabolites in XHP were classified as phospholipids and amino acids, steroid hormones and carboxylic acids . KEGG functional pathways main involved are Lipid metabolism, Amino acid metabolism, Cancer: overview. KEGG enrichment and topology analysis, mainly involved in steroid hormone biosynthesis pathway and beta-alanine metabolism pathway. Conclusion. The main differential metabolite of XHP in rat serum may be Abscisic acid. XHP may exert its pharmacological effect on breast cancer by regulating steroid hormone biosynthesis pathway to regulate estrogen and progesterone levels and beta-alanine metabolism pathway to induce cancer cell apoptosis.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-11-23
Abstract: Objective To explore the clinical effect of external application of mirabilite on periappendiceal abscess with yin-damaging syndrome caused by heat toxicity.Methods 60 cases of periappendiceal abscess diagnosed as heat-toxic yin-damaging syndrome were randomly divided into treatment group and control group. The control group was treated with conventional antibiotics for 1~2 weeks, while the treatment group was treated with external application of mirabilite on the basis of the control group. The total effective rate, time for body temperature to return to normal, time for abdominal pain relief, time for abscess reduction, time for white blood cell count to return to normal, hospitalization time and patient satisfaction were compared between the two groups.Results The total effective rate in the treatment group was 93.33%, which was significantly higher than that in the control group (73.33%), and the difference in curative effect was statistically significant (P<0.05). Compared with the control group, the total effective rate, the time for body temperature to return to normal, the time for abdominal pain relief, the time for abscess reduction, the time for white blood cell count to return to normal, the hospital stay and the patient satisfaction of the two groups were better in the treatment group (P<0.05).Conclusion The external application of mirabilite in treating periappendiceal abscess with yin-damaging syndrome due to heat toxicity can enhance the curative effect, relieve patients' pain, shorten hospitalization time and improve patients' satisfaction with nursing, and the operation method is simple and safe, which is worthy of wide clinical application.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-11-03
Abstract: This article reviews the clinical nursing of one patient with lumbar disc herniation syndrome treated with Chinese herbal ointment, and summarizes the nursing experience. Through the accurate nursing assessment of patients, the nursing goals of patients are clarified, and on the basis of routine nursing and health education, through the implementation of Chinese herbal ointment technology, it can effectively improve patients' pain and lower limb weakness. Traditional Chinese medicine ointment for the treatment of lumbar and lumbar disc herniation syndrome has obvious clinical efficacy, and has few adverse reactions, which is easy for patients to accept.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-09-04
Abstract: Objetive Based on text mining technology and network pharmacology, to explore the TCM syndrome-drug rule in "Diagnosis and Treatment Program for COVID-19". Methods Based on the "Diagnosis and Treatment Program for COVID-19" (hereinafter referred to as the "Program") obtained by searching for "Program" on the official website of the National Health and Medical Commission, the relevant information on symptoms and pre
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-08-28
Abstract: Purpose : Exploring the mechanism and material basis of function of Sophora japonica in treating cirrhosis based on bioinformatics.
method : LC-MS acquired the ingredients of traditional Chinese medicine, using SuperPred and TTD databases to screen out the targets of action of Chinese medicine and disease respectively; Venny database was used for intersection analysis; A network diagram was constructed through Cytoscape software; Metoscape database was used for GO and KEGG enrichment analysis; CB-DOCK2 software completed molecular docking.
result : Through experimental screening, 85 ingredients and 46 intersection targets were found to have therapeutic effects on diseases. The core targets include HIF1A, TNF-a, PTGS2, MAPK1, etc. It is mainly related to cancer pathways, apoptosis, lipid, and atherosclerosis signal pathways for the treatment of cirrhosis by Sophora Tonkinensis Gagnep.
conclusion : Using bioinformatics methods to predict the mechanism of action and material basis of Sophora Tonkinensis Gagnep in treating cirrhosis, providing new ideas and clues for its further research.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-08-28
Abstract: Objective Research on the mechanism and substance basis of Eucommia Folium treating epilepsy based on bioinformatics technology. Methods Using LC-MS technology to obtain the components of Eucommiae Folium, and obtaining the components and disease targets through the SuperPred database and GeneCards database. Using Cytoscape software to establish network maps; Perform enrichment analysis using Metascape database; Use CB-dock software for molecular docking. Results A total of 113 active ingredients and 531 target points were screened from the Eucommiae Folium, with 29880 epilepsy disease target points, 57 intersection target points and nine core target points. The main related signaling pathways include cancer pathways, serotonin synapse, etc. Conclusions The mechanism of Eucommiae Folium in treating epilepsy may be related to inflammation response, providing a scientific theoretical basis for further pharmacological experiments.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica Subjects: Linguistics and Applied Linguistics >> Linguistics and Applied Linguistics submitted time 2023-07-13
Abstract: Late summer is an important term in Chinese medicine. Among the ancient medical scholars, only Gao Shizong was found to have clearly explained the pronunciation of the word "late" in late summer. In order to clarify the pronunciation of the character "Chang" of Changxia, we searched the ancient classical Chinese medical texts, sorted through the existing literature and analyzed the views of existing scholars, and on this basis, we proposed a new opinion that when the character "late" is pronounced zhǎng, it means that the elders are honored; when it is pronounced cháng, it means that the elders are honored. When pronounced cháng, it expresses the good wish of life and vitality for a long time and the long duration of time, and it also indicates the longest state of the yellow bell. The clarification of the pronunciation of late summer can help to further understand Changxia and help to further interpret and study Chinese medicine.
Peer Review Status:Awaiting Review
Subjects: Psychology >> Other Disciplines of Psychology Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-05-29
Abstract: Objective:In order to consolidate the level of peoples spiritual cultivation in China, experts of philosophy of mind and TCM in the Ming Dynasty in Lingnan area were interviewed with a self-made interview outline to investigate the extended characteristics of spiritual cultivation in the form of interviews and online voice interviews, in order to make preliminary preparations for the development of the scale of mental cultivation accomplishment. Methods: In LingNan region of Ming dynasty study experts and TCM experts (a total of 8) as the interview consulting object, using the homemade interview outline, to interview and online voice interview, the study of mental characteristics, and adopt the qualitative analysis software Nvivo20 to analyze the interview manu
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-01-20
Abstract:
Gastric cancer is a common gastrointestinal malignancy, and reducing the incidence and mortality of gastric cancer is a major public health problem that needs to be addressed urgently. The application of pharmacological interventions for precancerous states and lesions of the stomach is one of the important aspects of gastric cancer prevention, and recent studies have shown that Chinese medicine has unique advantages in this regard. In this review, we list the possible targets and mechanisms of action of TCM acupuncture or herbal formulations by compiling the understanding and therapeutic tools related to the treatment of gastric precancerous lesions, with a focus on their immunotherapeutic mechanisms. This study contributes to the understanding of the potential role of TCM multi-target and multi-pathway interventions of the immune system in gastric precancerous lesions, and also provides an outlook on the possible new targets and pathways.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-01-20
Abstract:
China is a region with high incidence of myopia. The incidence of myopia in adolescents is increasing year by year, and it is gradually developing towards a younger age. Moreover, the pressure of further education and the popularization of electronic products will also have a continuous impact on the prevalence of myopia. Myopia causes serious damage to the physical and mental health of adolescents, and adolescent myopia has become the focus of prevention and control of myopia. At present, western medicine treatment of myopia includes wearing glasses, atropine, and surgical treatment, but there are many side effects, and cannot fundamentally solve the pathological changes caused by myopia. Chinese medicine has a long history of treating myopia. At present, the treatment of myopia in traditional Chinese medicine mainly includes traditional Chinese medicine, acupuncture, massage, ear acupuncture, comprehensive therapy, etc. All of which can improve the myopia of patients to a certain extent, and have the advantages of simplicity, safety, and no side effects. This paper studies the understanding of the theory of myopia in TCM in recent years summarizes the treatment plan of myopia, and summarizes the current problems in the clinical treatment of myopia, to provide a more effective method for the treatment of myopia by TCM, and give full play to the advantages of TCM treatment of non-disease.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2023-01-20
Abstract:
This paper summarizes the current research status of TCM nursing quality evaluation from the aspects of TCM nursing quality evaluation model, TCM nursing quality evaluation index, TCM nursing quality evaluation tools and methods, and puts forward some views on the construction of TCM nursing quality evaluation system, so as to provide support for the construction of TCM nursing quality evaluation system.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica Subjects: Psychology >> Social Psychology submitted time 2022-07-30
Abstract: Objective To collate and analyze the current status of published tools for TCM quality of life assessment, to provide a reference for researchers to select appropriate tools for TCM quality of life assessment, and to develop and improve tools for TCM quality of life assessment. Methods The TCM life quality assessment tools since the establishment of CNKI, Wanfang Database, and VIP Database were retrieved, and the retrieval results were organized and counted. Results A total of 57 assessment tools for Chinese medicine quality of life were retrieved. The development time of each assessment tool ranged from 2015 to 2019, and the number of items was mainly distributed in the range of 30 to 60. There were 51 assessment tools with good reliability after the reliability test, mainly in the physiological, psychological, social, and life dimensions. Limitations Due to the late development of some evaluation tools, their application effects need further study. Conclusion The dimensions and item division of different TCM life quality assessment tools are different, so more attention should be paid to a standard evaluation in developing TCM life quality assessment tools. Objective To collate and analyze the current status of published tools for TCM quality of life assessment, to provide a reference for researchers to select appropriate tools for TCM quality of life assessment, and to develop and improve tools for TCM quality of life assessment. Methods The TCM life quality assessment tools since the establishment of CNKI, Wanfang Database, and VIP Database were retrieved, and the retrieval results were organized and counted. Results A total of 57 assessment tools for Chinese medicine quality of life were retrieved. The development time of each assessment tool ranged from 2015 to 2019, and the number of items was mainly distributed in the range of 30 to 60. There were 51 assessment tools with good reliability after the reliability test, mainly in the physiological, psychological, social, and life dimensions. Limitations Due to the late development of some evaluation tools, their application effects need further study. Conclusion The dimensions and item division of different TCM life quality assessment tools are different, so more attention should be paid to a standard evaluation in developing TCM life quality assessment tools.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2022-07-30
Abstract: Objective Diabetic nephropathy is the most common and serious microvascular complication of diabetes and has become the primary cause of end-stage renal disease in developed countries and regions. Assessment of the efficacy of diagnosis and treatment of traditional Chinese medicine is conducive to the joint management of the symptoms. Methods This paper reviews the content, characteristics, and application of traditional Chinese medicine evaluation methods for the clinical efficacy of patients with diabetic nephropathy on hemodialysis. Results Efficacy evaluation criteria can be summarized as follows: patients' conscious improvement is taken as the efficacy evaluation criteria; doctors' judgment on improvement is taken as the efficacy evaluation criteria; and self-made efficacy evaluation criteria. Limitations Due to the late development of some evaluation tools, their application effects need further study. Conclusion It was suggested that according to the characteristics of the existing universal tools and in combination with the disease characteristics of patients with diabetic nephropathy on hemodialysis, a specific efficacy evaluation tool for patients with diabetic nephropathy on hemodialysis be developed to provide the basis for improving the treatment of diabetic nephropathy by effective management.
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2020-05-05
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease. Wasp venom (WV) relieves rheumatoid arthritis considered as a traditional folk medicine in Jingpo nationality in Yunnan, China. The current study aimed to investigate the effect of wasp venom ameliorating rheumatoid arthritis symptoms in experimental rats. We established a model of type II collagen (CII)-induced arthritis (CIA) in SD rats and examined the inhibition of inflammation and autoimmune response. The anti-arthritic effects of WV were evaluated through the paw swelling, histopathological score and histopathology changes of the affected paw were assessed. The anti-inflammation effects were assayed by the level of IL-6, TNF-α, IL-1β and the number of inflammatory cells in peripheral blood. The alteration of the T cell subsets ratio in the spleen of rats was detected by ?ow cytometry, at the same time the viscera index and immune serum globulin levels were evaluated. The results suggested that various doses of WV (0.125, 0.25 and 0.5 mg/kg) significantly alleviated paw swelling and arthritis score in CIA rats with the untreated control (P < 0.05). WV (0.25 and 0.5 mg/kg) relieved synovial tissue lesions of ankle joints and histopathology scores of synoviocyte hyperplasia and inflammatory cell infiltration with vehicle group (P < 0.05). Regarding immunological regulation, 0.5 mg/kg WV lowered the immune serum globulin levels (P < 0.05), and we further found that WV (0.5 mg/kg) suppressed the immune response of Th cells, while enhanced the functions of Tc cells and Treg cells in spleen cells markedly (P < 0.05). The immunosuppressive action of WV displayed was analogous to its inhibitory effect on IL-1β, TNF-α, IL-8, IL-6, COX-2 and PGE2 levels in rat serum. In conclusion, these findings demonstrated that WV exhibited anti-arthritic activity, which might be associated with their inhibitory effects on immunoregulation and anti-inflammatory action."
Peer Review Status:Awaiting Review
Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2020-01-16
Abstract: Chronic renal failure is the last stage of the progressive nephropathy,which include multiple complications and adverse prognosis. Symptomatic treatment is the main therapy, when diagnosed with uremia, only dialysis and kidney transplantation are available, which cost high medical expenses and heavy social burden. Professor Lyu Renhe has rich experience with ganoderma lucidum and rhodiola rosea in the treatment of chronic renal failure, Consequently we concluded and interpret that." " "
Peer Review Status:Awaiting Review
Subjects: Computer Science >> Natural Language Understanding and Machine Translation Subjects: Medicine, Pharmacy >> Traditional Chinese Medicine and Chinese Materia Medica submitted time 2019-10-15
Abstract: "
Peer Review Status:Awaiting Review