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  • Clinical Characteristics and Medication Patterns of Patients with Cardiometabolic Multimorbidity

    Subjects: Medicine, Pharmacy >> Clinical Medicine submitted time 2024-06-06 Cooperative journals: 《中国全科医学》

    Abstract: Background Cardiometabolic multimorbidity (CMM) was one of the most common comorbidity aggregation patterns in different regions and populations,with a high risk of mortality. However,studies on the clinical and medication characteristics of CMM were limited. Objective To study the clinical characteristics and medication patterns of patients with CMM in the real world,and provide reference basis for the prevention and management of CMM. Methods Outpatient patients who were diagnosed with cardiometabolic multimorbidity in the hospital information system(HIS)from January 2023 to June 2023 were selected. Basic prescription information was collected and analyzed using frequency analysis and association rule analysis methods. Results A total of 7 059 patients with CMM were included,of which 3 960(56.1%) were male and 3 099(43.9%) were female,with an age range of 18 to 97 years and a mean age of (58.1±13.7) years. The results showed that 3910 patients with less than 5 types of medication,accounting for 55.4%;2 740 patients with 5-9 types of medication,accounting for 38.8%;and 409 patients with more than 10 types of medication,accounting for 5.8%. Hypertension,dyslipidemia,and diabetes were the core diseases of CMM. Among the comorbidities of cardiovascular metabolic diseases,chronic gastritis,renal insufficiency,and hyperuricemia were more common. In the prescription of patients with CMM,statins,calcium channel blockers(CCB),angiotensin receptor blockers(ARB),metformin,and sodium-dependent glucose transporters 2 inhibitors(SGLT2i) were the core medications. Conclusion Our findings suggestchronic gastritis,renal insufficiency,and hyperuricemia are more common diseases in patients with CMM. Screening and prevention should be strengthened and treatment strategies should be adjusted. In the CMM drug prescription,lipid-lowering, antihypertensive,and hypoglycemic drugs are the core drugs used.

  • Parental Phubbing and Adolescent Online Game Addiction:The Mediating Role of Deviant Peer Interaction

    Subjects: Psychology >> Developmental Psychology submitted time 2024-01-15

    Abstract: Objective: To explore the relationship between parental phubbing and adolescent onlinegameaddiction and the mediating role of deviant peer interaction. Methods: 808 adolescents were investigatedbyparentalphubbing scale, deviant peer interaction scale and online game addiction scale. AMOS26.0 was usedtotest themediating effect. Results: Parental phubbing was positively correlated with online game addiction (r=0.23, p<0.01)and deviant peer interaction (r=0.19, p<0.01), and deviant peer interaction was positively correlated withonlinegame addiction (r=0.23, p<0.01). Deviant peer interaction plays a partial mediating role between parents' lowerself-esteem and online game addiction. Conclusion: Parental phubbing can not only directly affect onlinegameaddiction but also indirectly increase the risk of online game addiction by promoting deviant peer interaction.

  • Does male have more fear of missing out than female?A meta-analysis

    Subjects: Psychology >> Developmental Psychology submitted time 2024-01-15

    Abstract: Objective To explore gender difference and its influencing factors of fear ofmissing out. Methods Literature search was carried out in 12 databases in China and abroad. Atotal of 118 eligible studies (including 120 effect sizes) were selected by EndNoteX9, with a timespan from 2013 to 2023. CMA3.0 combined with random effects model was used for statisticalanalysis. Results The main effect analysis showed that the gender difference of FoMOwas notsignificant. The moderating effect showed that the female's FoMO was significantly higher thanthe male's in adolescence, but the opposite was true in adulthood. The FoMO is significantlyhigher in domestic men than in women, but the opposite is true in foreign countries. Using theSong Xiaokang version of the scale, the score of male FoMO was significantly higher than that offemale, while the other tools were opposite. The moderating effects of publication age andpublication type were not significant. Conclusion The gender difference in fear of missing out isaffected by age, sampling area, and measures of FoMO, so it is necessary to analyze the situationin scientific research and intervention.

  • 氮肥配施生化抑制剂对黄泥田土壤钾素淋溶特征的影响

    Subjects: Biology >> Ecology submitted time 2018-01-05 Cooperative journals: 《中国生态农业学报》

    Abstract: Soil nutrient leaching of yellow clayey soil, especially nitrogen (N) and potassium (K), is extremely serious in southern China. This resulted in not only resources waste and potential environmental threat, but also serious restriction of sustainable production of crops. In the present study, the effects of a urease inhibitor (N-(n-butyl) thiophosphoric triamide, NBPT), a nitrification inhibitor (2-chloro-6-(trichloromethyl) pyridine, CP) and their combined application on the leaching characteristics of soil potassium (K) in yellow clayey soil were investigated for improving the capability of soil K by fertilization, using an indoor soil column simulation with urea (U) and urea ammonium nitrate (UAN). In the leaching solution of different N fertilizers, the higher average K+ concentration was obtained by UAN treatment (103.0mg/kg) than that of U treatment (93.9mg/kg), and there were obviously differences among inhibitor treatments. At the end of incubation (Day 72), UAN treatment increased K+ leaching amount by 6.7% than that of U treatment. K+ accumulation of leaching solution among U treatments was in the range of U > U+NBPT > U+NBPT+CP > U+CP > CK. Compared with U treatment, U+NBPT, U+CP and U+NBPT+CP treatment in K+ accumulation were reduced by 8.7%, 20.2% and 14.9%, respectively. K+ accumulation among UAN treatments was in the range of UAN > UAN+NBPT > UAN+NBPT+CP > UAN+CP > CK. Compared with UAN treatment, UAN+NBPT, UAN+CP and UAN+NBPT+CP treatment in K+ accumulation were reduced by 6.0%, 13.8% and 9.2%, respectively. Additionally, the leaching rate of K+ across different treatments was in the range of UAN > UAN+NBPT > U > UAN+NBPT+CP > UAN+CP > U+NBPT > U+NBPT+CP > U+CP. In the middle of incubation (Day 36), soil available K content of fertilizer microsites for U and UAN treatments decreased significantly. Addition of CP effectively maintained high available K content in topsoil. Compared with addition of NBPT alone, combined with CP can reduce NO3- leaching, and increase K+ fixed by soil lattice, and mitigate the leaching risk of K+ for more than 72 days in yellow clayey soil. Equation models were used to describe the relationship between K+ accumulation (y) and NO3- accumulation (x) of leaching solution. The linear equation (y = ax+b) and Elovich equation (y = alnx+b) fit well, a and b values for inhibitor treatments were obviously different. In conclusion, application of CP alone or combined with NBPT in yellow clayey soil can effectively increase the adsorption of K+, minimize soil K+ leaching loss, mitigate the risk of nutrient leaching, and improve fertilizer utilization rate.