分类： 医学、药学 >> 基础医学 提交时间： 2017-12-07 合作期刊: 《南方医科大学学报》
摘要： Objective To investigate the incidence of C5 nerve root palsy after multi-segmental cervical decompression through different approaches. Methods This study was conducted among 375 patients undergoing multi-segmental cervical decompression in anterior corpectomy and fusion fixation, anterior cervical corpectomy and fusion fixation+posterior decompression and fusion fixation, posterior cervical laminectomy decompression, fusion and internal fixation, and posterior laminoplasty and fusion groups. The exclusion criteria included lack of follow-up data, spinal cord injury preventing preoperative or postoperative motor testing, or surgery not involving the C5 level. The incidence of C5 palsy was determined and the potential risk factors C5 palsy were analyzed including age, sex, revision surgery preoperative weakness, diabetes smoking, number of levels decompressed, and a history of previous upper extremity surgery. Results Of the 375 patients, 60 patients were excluded and the data of 315 patients were analyzed, including 146 women and 169 men with a mean age of 57.7 years (range 39-72 years). The overall incidence of C5 nerve palsy was 6.03% (19/315) in these patients; in the subgroups receiving different surgeries, the incidence was 8.62% in the cervical road laminectomy and fusion fixation group, 7.79% in the anterior cervical corpectomy and fusion fixation+posterior decompression and fusion and internal fixation, 4.68% in the anterior corpectomy and fusion fixation group, and 3.85% in the posterior laminoplasty and fusion group. No significant difference was found in the incidences among the subgroups, but men were more likely than women to develop cervical nerve root palsy (8.28% vs 3.42%, P<0.05). Conclusion The overall incidence of C5 nerve palsy following postoperative cervical spinal decompression was 6.03% in our cohort. The incidence of C5 nerve palsy did not differ significantly following different cervical decompression surgeries, but the incidence was the highest in the posterior cervical laminectomy and fusion and internal fixation group.
分类： 医学、药学 >> 临床医学 提交时间： 2023-10-09 合作期刊: 《中国全科医学》
摘要： Takayasu's arteritis（TA） is a chronic granulomatous vasculitis mainly affecting the aorta and its major branches, which can cause stenosis, occlusion and aneurysm formation, severely influencing the affected women of childbearing age. TA has been extensively studied to be stable during pregnancy, but it may lead to pregnancy complications such as gestational hypertension, pre-eclampsia, preterm delivery, and intrauterine growth restriction. To reduce the adverse effects of TA on the mother and fetus, it is essential to control the disease activity during pregnancy. This article details the effects of TA on the reproductive system, its interaction with pregnancy and effects on the fetus, discusses the management measures during pregnancy and the perinatal period in patients of childbearing age with TA, providing guidance for improving multidisciplinary management and clinical outcomes in these patients.
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