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1. chinaXiv:201711.02434 [pdf]

A?Machine?Learning?Assisted,?Label-free,?Non-invasive?Approach?for?Somatic?Reprogramming?inInduced?Pluripotent?Stem?Cell?Colony?Formation?Detection?and?Prediction

Fan, K?(Fan, Ke); Zhang, S?(Zhang, Sheng); Zhang, Y?(Zhang, Ying); Lu, J?(Lu, Jun); Holcombe, M?(Holcombe, Mike); Zhang, X?(Zhang, Xiao)
Subjects: Biology >> Ecology

During cellular?reprogramming, the mesenchymal-to-epithelial transition is accompanied by changes?in?morphology, which occur prior to iPSC?colony?formation. The current?approach?for?detecting morphological changes associated with?reprogramming?purely relies on human experiences, which involve intensive amounts of upfront training, human error with limited quality control and batch-to-batch variations. Here, we report?a?time-lapse-based bright-field imaging analysis system that allows us to implement?a?label-free,?non-invasive?approach?to measure morphological dynamics. To automatically analyse and determine iPSC?colony?formation,?a?machine?learning-based classification, segmentation, and statistical modelling system was developed to guide?colony?selection. The system can detect and monitor the earliest cellular texture changes after the induction of?reprogramming?in?human?somatic?cells on day 7 from the 20-24 day process. Moreover, after determining the?reprogramming?process and iPSC?colony?formation?quantitatively,?a?mathematical model was developed to statistically predict the best iPSC selection phase independent of any other resources. All the computational?detection?and?prediction?experiments were evaluated using?avalidation dataset, and biological verification was performed. These algorithm-detected colonies show no significant differences (Pearson Coefficient)?in?terms of their biological features compared to the manually processed colonies using standard molecular approaches.

submitted time 2017-11-17 Hits717Downloads435 Comment 0

2. chinaXiv:201711.00041 [pdf]

Circulating Fluidized Bed Gasification of Low Rank Coal: Influence of O-2/C Molar Ratio on Gasification Performance and Sulphur Transformation

Zhang, H. X.,; Zhang, Y. K., ; Zhu, Z. P. ; Lu, Q. G.
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.

To promote the utilization efficiency of coal resources, and to assist with the control of sulphur during gasification and/or downstream processes, it is essential to gain basic knowledge of sulphur transformation associated with gasification performance. In this research we investigated the influence of O-2/C molar ratio both on gasification performance and sulphur transformation of a low rank coal, and the sulphur transformation mechanism was also discussed. Experiments were performed in a circulating fluidized bed gasifier with O-2/C molar ratio ranging from 0.39 to 0.78 mol/mol. The results showed that increasing the O-2/C molar ratio from 0.39 to 0.78 mol/mol can increase carbon conversion from 57.65% to 91.92%, and increase sulphur release ratio from 29.66% to 63.11%. The increase of O-2/C molar ratio favors the formation of H2S, and also favors the retained sulphur transforming to more stable forms. Due to the reducing conditions of coal gasification, H2S is the main form of the released sulphur, which could be formed by decomposition of pyrite and by secondary reactions. Bottom char shows lower sulphur content than fly ash, and mainly exist as sulphates. X-ray photoelectron spectroscopy (XPS) measurements also show that the intensity of pyrite declines and the intensity of sulphates increases for fly ash and bottom char, and the change is more obvious for bottom char. During CFB gasification process, bigger char particles circulate in the system and have longer residence time for further reaction, which favors the release of sulphur species and can enhance the retained sulphur transforming to more stable forms.

submitted time 2017-11-02 From cooperative journals:《热科学学报》 Hits530Downloads275 Comment 0

3. chinaXiv:201706.00731 [pdf]

Effect of Marangoni Number on Thermocapillary Convection and Free-Surface Deformation in Liquid Bridges

Zhang, Y [ 1 ]; Huang, HL [ 1 ]; Zhou, XM [ 2 ]; Zhu, GP [ 1 ]; Zou, Y [ 1 ]
Subjects: Dynamic and Electric Engineering >> Engineering Thermophysics

Floating zone technique is a crucible-free process for growth of high quality single crystals. Unstable thermocapillary convection is a typical phenomenon during the process under microgravity. Therefore, it is very important to investigate the instability of thermocapillary convection in liquid bridges with deformable free-surface under microgravity. In this works, the Volume of Fluid (VOF) method is employed to track the free-surface movement. The results are presented as the behavior of flow structure and temperature distribution of the molten zone. The impact of Marangoni number (Ma) is also investigated on free-surface deformation as well as the instability of thermocapillary convection. The free-surface exhibits a noticeable axisymmetric (but it is non-centrosymmetric) and elliptical shape along the circumferential direction. This specific surface shape presents a typical narrow 'neck-shaped' structure with convex at two ends of the zone and concave at the mid-plane along the axial direction. At both theta = 0 degrees and theta = 90 degrees, the deformation ratio increases rapidly with Ma at first, and then increases slowly. Moreover, the hydrothermal wave number m and the instability of thermocapillary convection increase with Ma.

submitted time 2017-06-22 From cooperative journals:《热科学学报》 Hits654Downloads311 Comment 0

4. chinaXiv:201705.00514 [pdf]

A co-confined carbonization approach to aligned nitrogen-doped mesoporous carbon nanofibers and its application as an adsorbent

Chen, AB [Chen, Aibing][ 1 ]; Liu, C [Liu, Chao][ 2 ]; Yu, YF [Yu, Yifeng][ 1 ]; Hu, YQ [Hu, Yongqi][ 1 ]; Lv, HJ [Lv, Haijun][ 1 ]; Zhang, Y [Zhang, Yue][ 1 ]; Shen, SF [Shen, Shufeng][ 1 ]; Zhang, J [Zhang, Jian][ 3 ]
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.

Nitrogen-doped carbon nanofibers (MCNFs) with an aligned mesoporous structure were synthesized by a co-confined carbonization method using anodic aluminum oxide (AAO) membrane and tetraethy- lorthosilicate (TEOS) as co-confined templates and ionic liquids as the precursor. The as-synthesized MCNFs with the diameter of 80–120 nm possessed a bulk nitrogen content of 5.3 wt% and bimodal meso- porous structure. The nitrogen atoms were mostly bound to the graphitic network in two forms, i.e. pyridinic and pyrrolic nitrogen, providing adsorption sites for acidic gases like SO2 and CO2 . Cyclic exper- iments revealed a considerable stability of MCNFs over 20 runs of SO2 adsorption and 15 runs for CO2 adsorption. The MCNFs also have a preferable adsorption performance for Cd2+.

submitted time 2017-05-02 Hits813Downloads380 Comment 0

5. chinaXiv:201705.00417 [pdf]

Lithium-assisted exfoliation of pristine graphite for few-layer graphene nanosheets

Xu, MW [Xu, Minwei][ 1,2 ]; Sun, HT [Sun, Huiting][ 1 ]; Shen, C [Shen, Cai][ 3 ]; Yang, S [Yang, Sen][ 1 ]; Que, WX [Que, Wenxiu][ 2 ]; Zhang, Y [Zhang, Yin][ 4 ]; Song, XP [Song, Xiaoping][ 1 ]
Subjects: Physics >> General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.

A lithium-assisted approach has been developed for the exfoliation of pristine graphite, which allows the large-scale preparation of few-layer graphene nanosheets. The process involves an unexpected physical insertion and exfoliation, and the graphene nanosheets prepared by this method reveal undisturbed sp2-hybridized structures. A possible two-step mechanism, which involves the negative charge being trapped around the edges of the graphite layers and a subsequent lithiation process, is proposed to explain the insertion of lithium inside the graphite interlayers. If necessary, the present exfoliation can be repeated and thinner (single or 2–3 layer) graphene can be achieved on a large scale. This simple process provides an efficient process for the exfoliation of pristine graphite, which might promote the future applications of graphene.

submitted time 2017-05-02 Hits575Downloads359 Comment 0

6. chinaXiv:201705.00311 [pdf]

Co-Precipitation Synthesis of Gadolinium Aluminum Gallium Oxide [GAGG] via Different Precipitants

Sun, Y [Sun, Yan][ 1,2 ]; Yang, SH [Yang, Shenghui][ 1 ]; Zhang, Y [Zhang, Ye][ 1 ]; Jiang, J [Jiang, Jun][ 1 ]; Jiang, HC [Jiang, Haochuan][ 1 ]

In order to obtain a uniform transparent ceramic scintillator, well-dispersed fine starting powders with high-purity, small grain size, spherical morphology and high sinter-ability are necessary. In this study, Ce3+ doped gadolinium aluminum gallium garne

submitted time 2017-05-02 Hits354Downloads219 Comment 0

7. chinaXiv:201705.00293 [pdf]

Aqueous-phase synthesis of nitrogen-doped ordered mesoporous carbon nanospheres as an efficient adsorbent for acidic gases

Chen, AB [Chen, Aibing][ 1 ]; Yu, YF [Yu, Yifeng][ 1 ]; Zhang, Y [Zhang, Yue][ 1 ]; Zang, WW [Zang, Wenwei][ 1 ]; Yu, YH [Yu, Yunhong][ 1 ]; Zhang, YX [Zhang, Yexin][ 2 ]; Shen, SF [Shen, Shufeng][ 1 ]; Zhang, J [Zhang, Jian][ 2 ]

Nitrogen-doped ordered mesoporous carbon spheres [N-OMCs] were conveniently produced by using a soluble urea-phenol-formaldehyde resin as the precursor and triblock copolymer F127 as a soft template. The obtained carbon spheres with a mean diameter of aro

submitted time 2017-05-02 Hits494Downloads306 Comment 0

8. chinaXiv:201703.00969 [pdf]

The Effects of Cation Concentration in the Salt Solution on the Cerium Doped Gadolinium Gallium Aluminum Oxide Nanopowders Prepared by a Co-precipitation Method

Yang, SH; Sun, Y; Chen, XQ; Zhang, Y; Luo, ZH; Jiang, J; Jiang, HC
Subjects: Materials Science >> Materials Science (General)

Cerium doped gadolinium gallium aluminum oxide (GAGG:Ce) nanopowders were prepared by a co-precipitation method with different cation concentrations of the mother salt solution, followed by calcination at different temperatures. The influence of cation co

submitted time 2017-03-30 Hits1103Downloads380 Comment 0

9. chinaXiv:201703.00934 [pdf]

The Effects of Cation Concentration in the Salt Solution on the Cerium Doped Gadolinium Gallium Aluminum Oxide Nanopowders Prepared by a Co-precipitation Method

Yang, SH; Sun, Y; Chen, XQ; Zhang, Y; Luo, ZH; Jiang, J; Jiang, HC
Subjects: Materials Science >> Materials Science (General)

Cerium doped gadolinium gallium aluminum oxide (GAGG:Ce) nanopowders were prepared by a co-precipitation method with different cation concentrations of the mother salt solution, followed by calcination at different temperatures. The influence of cation co

submitted time 2017-03-30 Hits750Downloads377 Comment 0

10. chinaXiv:201612.00440 [pdf]

A SM-like Higgs near 125 GeV in low energy SUSY: a comparative study for MSSM and NMSSM

Cao,J; Heng,Z; Yang,JM; Zhang,Y; Zhu,J
Subjects:

Motivated by the recent LHC hints of a Higgs boson around 125 GeV, we assume a SM-like Higgs with the mass 123-127 GeV and study its implication in low energy SUSY by comparing the MSSM and NMSSM. We consider various experimental constraints at 2-sigma le

submitted time 2016-12-28 Hits1351Downloads723 Comment 0

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