Subjects: Statistics >> Social Statistics submitted time 2023-06-15 Cooperative journals: 《中国科学院院刊》
Abstract：党的二十大报告指出，教育、科技、人才是全面建设社会主义现代化国家的基础性、战略性支撑。实现高水平科技自立自强关键靠人才，制度创新要聚焦大胆选拔和放手使用优秀青年人才，支持青年人才挑大梁、当主角。文章聚焦新时代创新人才的责任与使命，从青年科研人员通过自我修炼力争成为新时代所需的创新人才的路径，以及所在单位为其打造更好的成长环境两个角度给出了建议。
Subjects: Other Disciplines >> Synthetic discipline submitted time 2023-03-28 Cooperative journals: 《中国科学院院刊》
Abstract： In order to better participate in the international digital development, it is crucial to investigate the internal digital governance pattern of various countries and clarify their internal generation logic on the basis of recognizing the current situation. This work makes a comparative study of the internal digital governance patterns in China, the United States and European Union from the perspective of digital ecology, attempts to clarify their respective digital ecological development models, and analyzes the relationship between the development models and their digital regulation systems. The study found that the United States has formed a development model taking the lead in all aspects and a regulation system centered on encouraging innovation. The diversified development model of EU member countries has affected the EU to form a regulation system centered on market construction. China’s development model shows the characteristics of being application#2;driven, and the regulation system takes development and security as the dual core. Based on this, the study puts forward suggestions on how to optimize and adjust China’s digital regulation system, as well as transform and upgrade its digital ecological development model.
Subjects: Geosciences >> Geography submitted time 2021-08-01 Cooperative journals: 《干旱区地理》
Abstract： 准确、及时地绘制森林地上碳密度图是了解全球碳循环的必要条件。虽然星载激光雷达 （如 ICESat/GLAS）数据已被广泛用于估算大尺度的森林地上碳密度分布，但地形坡度对 GLAS 提取 冠层高度精度的影响往往限制了其在山区森林的应用。通过以祁连山国家公园为研究区域，结合GLAS 数据、Landsat OL（IOperational land imagery）数据、样地调查数据，对祁连山地区进行区域性的森林地上碳密度估算。首先通过改进后的地形校正模型减小坡度对 GLAS 数据提取森林冠层高度 精度的影响，使得更多的 GLAS 数据可用于后续的研究；其次将所建立的不同类型森林地上生物量 估算模型与相关碳含量转换系数结合，得到 GLAS 激光光斑（脚印点）的森林地上碳密度；最后利用 非参数化算法最大熵（MaxEnt）模型得到祁连山国家公园 2018 年森林地上碳密度分布图。结果表 明：祁连山国家公园 2018 年平均森林地上碳密度为 40.72±6.72 t·hm-2，总蓄积量为 28.58±4.72 Tg， 海拔 2770~3770 m 区域的森林植被碳储量最大，且阴坡的碳储量明显高于阳坡。采用森林资源清 查数据独立验证估算结果的准确性，模型估测均方根误差（Root mean square error，RMSE）为 18.946 t·hm-2。本研究结果可以为监测区域乃至国家尺度的森林碳储量变化以及制定可持续的森林管理 措施提供依据。此外，本文所采用的方法在山区森林碳储量估算方面也具有较大的潜力。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-07 Cooperative journals: 《南方医科大学学报》
Abstract： Objective To investigate the effect of simulated microgravity on erythroid differentiation of K562 cells and explore the possible mechanism. Methods The fourth generation rotating cell culture system was used to generate the simulated microgravity environment. Benzidine staining was used to evaluate the cell inhibition rate, and real-time quantitative PCR (qRT-PCR) was used to detect GATA-1, GATA-2, Ets-1, F-actin, β-Tubulin and vimentin mRNA expressions. The changes of cytoskeleton were observed by fluorescence microscopy, and Western blotting was employed to assay F-actin, β-tubulin and vimentin protein expression levels. Results Benzidine staining showed that simulated microgravity inhibited erythroid differentiation of K562 cells. K562 cells treated with Hemin presented with increased mRNA expression of GATA-1 and reduced GATA-2 and Ets-1 mRNA expressions. Simulated microgravity treatment of the cells resulted in down-regulated GATA-1, F-actin, β-tubulin and vimentin mRNA expressions and up-regulated mRNA expressions of GATA-2 and Ets-1, and reduced F-actin, β-tubulin and vimentin protein expressions. Exposure to simulated microgravity caused decreased fluorescence intensities of cytoskeletal filament F-actin, β-tubulin and vimentin in the cells. Conclusion Simulated microgravity inhibits erythroid differentiation of K562 cells possibly by causing cytoskeleton damages to result in down-regulation of GATA-1 and up-regulation of GATA-2 and Ets-1 expressions.
Hits
Hits
Downloads
Comment