Subjects: Digital Publishing >> New Media submitted time 2023-10-08 Cooperative journals: 《中国传媒科技》
Abstract:随着科技的不断进步,信息技术的发展速度越来越快,社会各行各业信息数据量急速增加,对行业的发展产生了重要的影响。面对如此庞大的信息量大数据技术便应运而生。如何从这些信息里面找到更具有报道价值的新闻成为现在的主要发力点。可以通过大数据技术进行预测分析,对于市场行情的掌握有着重要的指导意义。应用到新闻行业中,大数据技术在新闻信息的手机、查询、分析和处理方面都可以发挥更大的作用。并且大数据技术对于这些信息的处理效率更高,分析能力更强,对于新闻行业的发展有着巨大的帮助作用。本文分析了大数据技术对新闻采写和编辑的影响,以期在新闻行业中的应用会起到一定作用。
Subjects: Biology >> Bioengineering submitted time 2018-06-14 Cooperative journals: 《中国生物工程杂志》
Abstract:近年来,趋磁细菌及其生物自身合成的磁小体由于良好的生物安全性逐渐被人们所认识,并被用于生物工程和医学应用研究。与人工化学合成磁性纳米颗粒相比,从趋磁细菌中提取的磁小体具有生物膜包被、生物相容性高、粒径均一以及磁性高等优势。趋磁细菌因磁小体在其胞内呈链状排列,具有沿磁场方向泳动的能力,也被应用于各种应用研究。因此,本文综述了趋磁细菌及磁小体特性,并就最近的研究进展重点综述趋磁细菌和磁小体在生物工程和医学应用等领域的最新研究进展。
Subjects: Geosciences >> Geography submitted time 2020-12-17 Cooperative journals: 《干旱区研究》
Abstract:在水分输入以小量级降水和凝结水为主导的干旱区,植物叶片吸收水分策略具有尤为重要的生态意义。以民勤地区20种荒漠植物为研究对象,测定叶片单位面积吸水量(LWUC)、含水量增加率(RW)、水分饱和亏(WSD)、比叶面积(SLA)、干物质含量(LDMC),分析植物各叶片性状的分布规律及其相互关系,并比较不同功能群植物叶片水分吸收性状的变异特征。结果表明:(1)叶片可以吸收水分,具有利用小量级降水的能力;叶片性状存在较大的种间差异。(2)叶片LWUC与LDMC呈极显著负相关(P<0.01),RW与WSD呈极显著正相关(P<0.01)。(3)不同生长型植物叶片LWUC、RW、WSD差异不显著(P>0.05)。(4)不同质地植物叶片LWUC差异极显著(P<0.01),其中,肉质多汁类型植物显著(P<0.05)高于草质、革质类型植物,肉质多汁和叶片退化类型植物差异不显著(P>0.05)。(5)不同叶面性状植物叶片LWUC差异不显著(P>0.05),但覆毛类型植物叶片RW、WSD极显著(P<0.01)高于光滑叶面平均值。总之,本研究可以加深对荒漠生态系统不同功能型植物利用水资源方式和策略的理解,增强对荒漠植物生态适应对策和荒漠植被格局变化的认识,并为其保护和恢复提供科学依据。
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2017-12-27 Cooperative journals: 《南方医科大学学报》
Abstract: Objective To explore the relations among apolipoprotein E4, Tau protein and glycogen synthase kinase 3β (GSK-3β).Methods U87 cells were transfected with pIRES-EGFP (control) or the recombinant plasmids ApoE4/pIRES-EGFP or ApoE3/ pIRES-EGFP, and the expression levels of p-Tau/Tau and GSK-3β in the cells were examined with Western blotting. To further confirm the effect of ApoE on GSK-3β and p-Tau expressions, a short interfering RNA (siRNA) targeting ApoE (ApoE-siRNA) was transfected into U87 cells via Lipofectamine 2000 and the protein expressions were examined 24 h later. Results Compared with those in the control group, the expressions levels of both GSK-3β and p-Tau/Tau increased significantly in the cells transfected with ApoE4 and ApoE3 plasmids (P<0.01), and the ApoE4 plasmid produced a more potent effect than the ApoE3 plasmid on the protein expressions (P<0.01). ApoE knockdown resulted in significantly reduced expressions of GSK-3β (P< 0.001) and p-Tau (P<0.01) in the cells. Conclusion ApoE4 can enhance Tau phosphorylation though upregulating GSK-3β, which sheds light on a new role of ApoE4 in Alzheimer's disease.
Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2022-10-13 Cooperative journals: 《中国全科医学》
Abstract: Background Previous studies have shown that the effect of non-invasive brain stimulation (NIBS) for autism spectrum disorder (ASD) is different, and there is a lack of comparison of the efficacy of different NIBS. Objective To systematically evaluate the effect of NIBS for ASD, and compare the curative effects of two different NIBS. Methods Randomized controlled trials about the effect of NIBS for autism spectrum disorder were retrieved from domestic and foreign databases, from inception to December 2021. After assessing the risk of bias of the included studies, the statistical analysis was performed using RevMan 5.3 and R 4.0.2 software. Results Ultimately, 22 studies involving 661 patients were included. Meta-analysis showed that NIBS could reduce autism behavior checklist (ABC) score (MD=-8.80, 95%CI -10.98~-6.62,P<0.05), childhood autism rating scale (CARS) score (MD=-2.93, 95%CI -3.63~-2.24, P<0.05), autism treatment evaluation checklist (ATEC) score (MD=-9.13, 95%CI -12.79~-5.47, P<0.05), self-rating anxiety scale (SAS) score (MD=-7.20, 95%CI -10.55~-3.85, P<0.05), self-rating depression scale (SDS) score (MD=-8.89, 95%CI -13.21~-4.57, P<0.05) and mismatch negative latentperiod (MD=-5.97, 95%CI -9.42~-2.53, P<0.05), and increase development quotient (DQ) score (MD=5.22, 95%CI 3.41~7.04, P<0.05) and mismatch negative amplitude (MD=1.54, 95%CI 0.57~2.51, P<0.05). Network meta-analysis showed that the best probabilistic ranking of the effects of two different NIBS on the pain score is transcranial direct current stimulation (tDCS) (P=0.93)>repetitive transcranial magnetic stimulation (rTMS) (P=0.06). Conclusion Existing evidence showed that NIBS could improve autism spectrum disorder, and that tDCS is better than rTMS.