Effects of Collagen Assembly Form on Biomimetic Mineralization

Subjects: Materials Science >> Materials Science (General) submitted time 2023-03-31 Cooperative journals: 《材料研究学报》

丁珊 唐敏健 陈俊杰 周长忍 李立华 李红

Abstract： To simulate the ordered texture of the collagen in natural bone tissue, membranes of collagen with hierarchically ordered texture were fabricated. The effect of templates made of collagen with and without ordered texture on the biomineralization process of calcium phosphate was comparatively studied in vitro. The morphology and structure of the deposited calcium phosphate on the collagen templates were characterized by using polarizing microscope (POM), scanning electron microscope (SEM), atomic force microscope (AFM) and X-ray diffraction (XRD). The results show that the collagen with hierarchically ordered texture has obvious effect on the biomimetic mineralization process; on which the deposited calcium phosphate is much more orderly and compact either in micro- or in macro scales. This result indicates that the collagen with hierarchically ordered texture is beneficial to the building of biomimetic bone tissues as materials for repair of human bone etc.

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