分类: 物理学 >> 基本粒子与场物理学 提交时间: 2016-05-08
摘要: We study the P - V criticality and phase transition in the extended phase space of charged Gauss-Bonnet black holes in anti-de Sitter space, where the cosmological constant. appears as a dynamical pressure of the system and its conjugate quantity is the thermodynamic volume of the black holes. The black holes can have a Ricci flat (k - 0), spherical (k = 1), or hyperbolic (k = -1) horizon. We find that for the Ricci flat and hyperbolic Gauss-Bonnet black holes, no P - V criticality and phase transition appear, while for the black holes with a. spherical horizon, even when the charge of the black hole is absent, the P - V criticality and the small black hole/large black hole phase transition will appear, but it happens only in d = 5 dimensions; when the charge does not vanish, the P - V criticality and the small black hole/large phase transition always appear in d = 5 dimensions; in the case of d >= 6, to have the P - V criticality and the small black hole/large black hole phase transition, there exists an upper bound for the parameter b = (alpha) over tilde vertical bar Q vertical bar(-2/(d-3)), where (alpha) over tilde is the Gauss-Bonnet coefficient and Q is the charge of the black hole. We calculate the critical exponents at the critical point and find that for all cases, they are the same as those in the van der Waals liquid-gas system.
分类: 物理学 >> 核物理学 提交时间: 2023-07-06
摘要: Proton computed tomography (CT) has a distinct practical significance in clinical applications. It eliminates 35% errors caused by the transformation of Hounsfield unit (HU) to relative stopping power (RSP) valueswhen using X-ray CT for positioning andtreatment planning systems (TPSs). Following the development of FLASH proton therapy, there are increased requirements for accurate and rapid positioning in TPSs. Thus, anewrapid proton CT imaging mode is proposed based on sparsely sampled projections. The proton beam wasboosted to 350 MeV by a compact proton linear accelerator (linac). In this study,thecomparisons of the proton scattering with the energyof 350 MeV and 230 MeV are conducted based on GEANT4simulations.Asthe sparsely sampledinformation associated with beam acquisitions at 12angles is not enough for reconstruction, X-ray CT is used as a prior image. The RSP map generated by converting the X-ray CT was constructed based onMonte Carlo simulations. Consideringtheestimationof the most likely path (MLP), the prior image-constrained compressed sensing (PICCS) algorithm isused to reconstruct images from twodifferent phantoms using sparse protonprojections of 350 MeV parallel proton beam. The results show that it is feasible to realize the proton image reconstruction with the rapid protonCT imaging proposed in this paper. It can produce RSP maps withmuchhigher accuracy for TPSs and fast positioning to achieve ultra-fast imaging for real-time image-guided radiotherapy(IGRT) in clinical proton therapyapplications.
分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要: The Monte Carlo method can be widely applied to particle transport through numerous simulated data processing operations. However, this process consumes much time. Traditional parallel computing based on multi-CPU or multi-core CPU can effectively address this issue, but it is limited by inadequate computer hardware. Nonetheless, the current programmability and parallel processing capability of digital graphics processing units (GPUs) can sustain general computing applications such as Monte Carlo program simulation. This paper presents a method that facilitates the parallel computation of the Monte Carlo procedure through GPUs. Its feasibility is verified through a sample of simplified photon transport program, the results indicate that execution time can be shortened by approximately 90 times. Based on the general Monte Carlo program Geant4, the photon and electronic coupled transport module was examined, analyzed, and rewritten using the GPU programming language OpenCL to generate a Geant4 parallel tool [base on GPU parallel computing tool (BOGPT)]. The simulation results of the standard examples demonstrated that the outcomes of the BOGPT program are similar to those of Geant4 and the simulation time can be reduced by approximately three times. Finally, the GPU programming-based parallel computing method for Monte Carlo applications is accelerated and implementation prospects are broadened following further optimization.
分类: 核科学技术 >> 辐射物理与技术 提交时间: 2024-04-19
摘要: The superconducting magnet system of a fusion reactor plays a vital role in plasma confinement, a processthat can be disrupted by various operational factors. A critical parameter for evaluating the temperature marginof superconducting magnets during normal operation is the nuclear heating caused by D-T neutrons. This studyinvestigates the impact of nuclear heating on a superconducting magnet system by employing an improvedanalysis method that combines neutronics and thermal hydraulics.In the magnet system, toroidal field (TF) magnets are positioned closest to the plasma and bear the highestnuclear-heat load, making them prime candidates for evaluating the influence of nuclear heating on stability.To enhance the modeling accuracy and facilitate design modifications, a parametric TF model that incorporatesheterogeneity is established to expedite the optimization design process and enhance the accuracy of the computations. A comparative analysis with a homogeneous TF model reveals that the heterogeneous model improvesaccuracy by over 12%. Considering factors such as heat load, magnetic-field strength, and cooling conditions,the cooling circuit facing the most severe conditions is selected to calculate the temperature of the superconductor. This selection streamlines the workload associated with thermal-hydraulic analysis. This approach enablesa more efficient and precise evaluation of the temperature margin of TF magnets. Moreover, it offers insightsthat can guide the optimization of both the structure and cooling strategy of superconducting magnet systems.
分类: 生物学 >> 生物物理学 >> 细胞生物学 提交时间: 2016-05-11
摘要: Membrane receptors at the surface of target cells are key host factors for virion entry; however, it is unknown whether trafficking and secretion of progeny virus requires host intracellular receptors. In this study, we demonstrate that dengue virus (DENV) interacts with KDEL receptors (KDELR), which cycle between the ER and Golgi apparatus, for vesicular transport from ER to Golgi. Depletion of KDELR by siRNA reduced egress of both DENV progeny and recombinant subviral particles (RSPs). Coimmunoprecipitation of KDELR with dengue structural protein prM required three positively charged residues at the N terminus, whose mutation disrupted protein interaction and inhibited RSP transport from the ER to the Golgi. Finally, siRNA depletion of class II Arfs, which results in KDELR accumulation in the Golgi, phenocopied results obtained with mutagenized prME and KDELR knockdown. Our results have uncovered a function for KDELR as an internal receptor involved in DENV trafficking.
分类: 天文学 >> 天文学 提交时间: 2023-02-19
摘要: Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor (GECAM) is a pair of microsatellites (i.e. GECAM-A and GECAM-B) dedicated to monitoring gamma-ray transients including gravitational waves high-energy electromagnetic counterparts, Gamma-ray Bursts, Soft Gamma-ray Repeaters, Solar Flares and Terrestrial Gamma-ray Flashes. Since launch in December 2020, GECAM-B has detected hundreds of astronomical and terrestrial events. For these bursts, localization is the key for burst identification and classification as well as follow-up observations in multi-wavelength. Here, we propose a Bayesian localization method with Poisson data with Gaussian background profile likelihood to localize GECAM bursts based on the burst counts distribution in detectors with different orientations. We demonstrate that this method can work well for all kinds of bursts, especially for extremely short ones. In addition, we propose a new method to estimate the systematic error of localization based on a confidence level test, which can overcome some problems of the existing method in literature. We validate this method by Monte Carlo simulations, and then apply it to a burst sample with accurate location and find that the mean value of the systematic error of GECAM-B localization is $\sim 2.5^{\circ}$. By considering this systematic error, we can obtain a reliable localization probability map for GECAM bursts. Our methods can be applied to other gamma-ray monitors.
分类: 天文学 >> 天文学 提交时间: 2023-02-19
摘要: Realtime trigger and localization of bursts are the key functions of GECAM, which is an all-sky gamma-ray monitor launched in Dec 10, 2020. We developed a multifunctional trigger and localization software operating on the CPU of the GECAM electronic box (EBOX). This onboard software has the following features: high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation, dedicated localization algorithm optimized for short and long bursts respetively, short time latency of the trigger information which is downlinked throught the BeiDou satellite navigation System (BDS). This paper presents the detailed design and deveopment of this trigger and localization software system of GECAM, including the main functions, general design, workflow and algorithms, as well as the verification and demonstration of this software, including the on-ground trigger tests with simulated gamma-ray bursts made by a dedicated X-ray tube and the in-flight performance to real gamma-ray bursts and magnetar bursts.