Pulse radiolysis of sparfloxacin in neutral aqueous solution 后印本

摘要: A pulse radiolysis study was carried out to investigate the radical anion and radical cation of sparfloxacin (SPAX). The reactions of SPAX with hydrate electron (e_aq^‒), hydroxyl radical (·OH) and azide radical (·N₃^‒) were investigated in this study. The transient absorption spectra of SPAX radical anion and SPAX radical cation were obtained. Two transient rate constants 2.2×10¹⁰ dm³·mol^‒1·s^‒1 and 1.7×10¹⁰ dm³·mol^‒1·s^‒1 for the reactions of SPAX with e_aq^‒ and ·OH were determined, respectively. Finally, based on the results obtained in this study, rational mechanisms of transient reactions were proposed.