Synergy of Human Immunodeficiency Virus Protease Inhibitors with Chloroquine against Plasmodium falciparum In Vitro and Plasmodium chabaudi In Vivo

作者： Zhengxiang He ¹ Li Qin ¹ Lili Chen ¹ Nanzheng Peng ¹ Jianlan You ¹ Xiaoping Chen ¹
作者单位：

1. Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences
提交时间：2017-05-10 14:00:57

摘要: The synergy of the activities between chloroquine and various human immunodeficiency virus protease inhibitors was investigated in chloroquine-resistant and -sensitive malaria parasites. In both in vitro and in vivo assay systems, ritonavir was found to be the most potent in potentiating the antimalarial action of chloroquine.

ANTIMALARIAL-DRUGS INTRACELLULAR GLUTATHIONE MALARIA PARASITES RESISTANCE ATOVAQUONE RITONAVIR REVERSAL CULTURE AGENTS

分类： 生物学 >> 生物医药
引用： ChinaXiv:201705.00719 (或此版本 ChinaXiv:201705.00719V1)
DOI:10.12074/201705.00719V1
CSTR:32003.36.ChinaXiv.201705.00719.V1
推荐引用方式： Zhengxiang He,Li Qin,Lili Chen,Nanzheng Peng,Jianlan You,Xiaoping Chen.(2017).Synergy of Human Immunodeficiency Virus Protease Inhibitors with Chloroquine against Plasmodium falciparum In Vitro and Plasmodium chabaudi In Vivo.中国科学院科技论文预发布平台.[ChinaXiv:201705.00719] (点此复制)

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2017-05-10 14:00:57

ChinaXiv:201705.00719V1

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