分类: 工程与技术科学 >> 工程与技术科学其他学科 提交时间: 2023-01-03 合作期刊: 《2022年第三届艺术设计、传播与工程科学研讨会》
摘要: Guided by the theory of landscape genes, this paper selected Daxu ancient town in Guilin as the research object, combined with field research, historical literature reference and other research methods, and based on the actual situation of the ancient town and the principle of gene division, constructed the landscape gene index system of Daxu ancient town based on environment, layout, architecture and cultural characteristics genes. The problems of landscape gene protection in Daxu Ancient Town were found. The gene system of street texture was not perfect and the landscape nodes were scattered. Cultural characteristic genes are disappearing, and historical and cultural resources are not deeply excavated and exploited. The protection of ethnic architectural genetic elements lags behind, and a large number of old houses are damaged. The paper puts forward that the traditional ancient towns in scenic spots should be protected and developed from the aspects of integrity, characteristics, authenticity and effective management mechanism.
分类: 光学 >> 量子光学 提交时间: 2023-02-19
摘要: The sensitivity of perturbation sensing can be effectively enhanced with higher-order exceptional points due to the nonlinear response to frequency splitting. However, the experimental implementation is challenging since all the parameters need to be precisely prepared. The emergence of exceptional surface (ES) improves the robustness of the system to the external environment, while maintaining the same sensitivity. Here, we propose the first scalable protocol for realizing photonic high-order exceptional surface with passive resonators. By adding one or more additional passive resonators in the low-order ES photonic system, the 3- or arbitrary N-order ES is constructed and proved to be easily realized in experiment. We show that the sensitivity is enhanced and experimental demonstration is more resilent against the fabrication errors. The additional phase-modulation effect is also investigated.
分类: 生物学 >> 生物医药 提交时间: 2017-05-10
摘要: This study was to investigate the effect of donor liver adenoviral cardiotrophin-1 (CT-1) gene transfer on early graft survival and function in rat small-for-size liver transplantation. We constructed a recombinant murine CT-1 adenoviral vector. Donor rats were transduced in vivo with adenoviruses expressing CT-1 (AdCT-1) or control vector (AdEGFP). Livers were harvested 4 days later, reduced to 40% of weight, and transplanted. A syngeneic rat orthotopic liver transplantation model was performed using 40% small-for-size grafts. Graft survival, liver function, hepatic architecture change, the degree of necrosis and apoptosis, and cell survival signaling pathways were assessed. AdCT-1 pretreatment markedly improved liver function and the survival of small-for-size grafts. In the CT-1 treatment group, hepatic architecture was well protected, apoptotic and necrotic cells were reduced; anti-apoptotic protein bcl-2 was up-regulated and proapoptotic cleaved caspase-3 was down-regulated, cell survival signaling pathways were activated by phosphorylation of protein kinase B (Akt), extracellular-regulated kinase (ERK) and Signal transducer and activator of transcription-3 (Stat- 3) after transplantation. In conclusion, donor liver adenoviral CT-1 transfer ameliorated ischemia/reperfusion injury by decreasing hepatic necrosis and apoptosis in small-for-size liver transplantation, mediated in part by activation of the Akt, ERK, and Stat-3 survival signaling pathways. These results may provide a potential clinical strategy to improve the outcome of small-for-size liver grafts.
分类: 物理学 >> 核物理学 提交时间: 2023-06-18 合作期刊: 《Nuclear Science and Techniques》
摘要: An improved method is proposed for the extraction of the symmetry energy coefficient relative to the temperature, asym/T, for the heavy-ion reactions near the Fermi energy region, based on the modified Fisher Model (MFM). This method is applied to the primary fragments of the Anti-symmetrized Molecular Dynamics (AMD) simulations for the reactions of 40Ca + 40Ca at 35 MeV/nucleon. The density and the temperature at the fragment formation stage are extracted using a self-consistent method.