Subjects: Biology >> Zoology submitted time 2018-12-25 Cooperative journals: 《动物营养学报》
Abstract：本试验在合成二氢杨梅素-镍配合物（DMY-Ni）的基础上探讨其作为饲料添加剂的饲用安全性。以二氢杨梅素（DMY）和乙酸镍为原料，采用加热回流法合成DMY-Ni，通过紫外光谱、红外光谱对其进行表征。采用噻唑蓝(MTT)法，研究不同浓度（10、20、40、80和160 g/mL）、不同作用时间（12、24、36和48 h）下，DMY与DMY-Ni对小鼠正常肝实质细胞AML12增殖的影响。结果显示：DMY与镍离子配合后可生成DMY-Ni。10、20和40 g/mL DMY或DMY-Ni分别作用AML12细胞48 h后，AML12细胞的存活率与空白对照组差异不显著（P>0.05）；80 g/mL及以上浓度的DMY-Ni作用AML12细胞48 h后，AML12细胞的存活率显著低于空白对照组（P<0.01或P<0.001），160 g/mL的DMY作用AML12细胞48 h后，AML12细胞的存活率显著低于空白对照组（P<0.01）。随DMY或DMY-Ni浓度的增加和作用时间的延长，AML12细胞的存活率逐渐降低。DMY与DMY-Ni对AML12细胞的半数抑制浓度（IC50）分别为285.1、222.84 g/mL。由此得出，DMY与DMY-Ni对AML12细胞都具有相对低毒性，且DMY-Ni对AML12细胞的毒性较DMY稍有增加。
Subjects: Geosciences >> Space Physics submitted time 2017-03-10
Abstract：本文选择参数化的电离层热层理论模型TIEGCM作为背景模型，基于COSMIC 掩星观测的电子密度廓线数据，应用集合卡尔曼滤波方法建立了全球电离层电子密度同化模型，实现了全球电离层的电子密度同化。同化结果表明，该同化模型能将观测资料有效地同化到背景模式中，获得全球三维电离层电子密度。与背景模式相比，同化得到的电子密度相对于观测值的偏差显著下降。此外，分组同化与同时同化的结果对比显示，平均偏差改善基本一致，同时同化后的标准偏差在峰值高度以上略有减小。
Peer Review Status:
Awaiting Review
Subjects: Geosciences >> Space Physics submitted time 2017-01-22
Abstract： Parameterized ionosphere model TIEGCM is used as background model. Basing on the COSMIC observations, global ionospheric electron density assimilation model is established using ensemble Kalman filter. Result shows, this model can effectively assimilate observations into background model and acquire three dimensional ionospheric electron density. Compared to background, the error between analysis and observations decreases significantly. The root mean square error(RMSE) of NmF2 decreases about 60% for observations assimilated, and 20% for observations not assimilated. The RMSE of hmF2 doesn’t get improvement except for mean error. The results of simultaneous assimilation (SA) and batches assimilation (BA) are compared for this case. The time that the two methods spend in assimilation is about 6 to 7 minutes, which does not differ very much. SA needs nearly 8 GB storage while BA less than 2GB. The statistic of electron density error shows that they nearly acquire the same mean error, but the SA gets relative better improvement in RMSE above 250km.
Peer Review Status:Awaiting Review
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