Subjects: Materials Science >> Materials Science (General) submitted time 2023-03-31 Cooperative journals: 《材料研究学报》
Abstract： The in vitro biocompatibility of a novel magnesium phosphate whisker (M-PW) was evaluated by real-time cellular analysis (RTCA) and Annexin-V/PI double marking methods, and its antibacterial property was evaluated by co-culture method. Results show that the in vitro biocompatibility of the MPW decreased with the increase of M-PW in the suspensions. It possessed excellent in vitro biocompatibility for the suspensions containing 500 μg/mL or lower amount of the M-PW. It had no toxic effect on osteoblast cells for the suspension with 50 and 200 μg/mL of M-PW respectively. The antibacterial efficacy of the suspensions increased with the increasing amount of M-PW. The antibacterial efficacy against Escherichia coli and Staphylococcus aureus achieved 96.84% and 99.93％ respectively for the suspension with 500 μg/mL of M-PW, demonstrating that the novel phosphorous-magnesium whisker possesses excellent antibacterial property.
Subjects: Materials Science >> Materials Science (General) submitted time 2023-03-18 Cooperative journals: 《材料研究学报》
Abstract： The in vitro biocompatibility (i.e. the cell proliferation and apoptosis of L929 cells) of 4 cast dental alloys (CoCrMo+1%Cu, CoCrMo+2%Cu, CoCrMo+3%Cu and CoCrMo) were evaluated by CCK-8 and Annexing-V/PI double marking methods to provide a biology reference in the clinical application of prosthodontics. Results show that the in vitro biocompatibility of 4 alloys decreases according to following sequence: CoCrMo+1%Cu, CoCrMo+2%Cu, CoCrMo and CoCrMo+3%Cu. However, the cytotoxicity grades of the 4 alloys are all ranked in level one, implying they are good enough in vitro biocompatibility.
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