Subjects: Statistics >> Social Statistics submitted time 2024-06-28 Cooperative journals: 《中国科学院院刊》
Abstract： The field of life sciences is rapidly evolving, driven by advancements in experimental techniques and vast biological big data which gradually arise and play an increasingly important role in life science research. First of all, biological big data has diversity and complexity, including genomic data, epigenomic data, proteomic data and other types. These data provide researchers with more comprehensive information and help reveal the laws behind life phenomena. Second, new data-driven developments and applications in life sciences cover many fields such as gene editing, precision medicine, drug development, etc., providing unprecedented possibilities for human health and quality of life. However, the era of big data for life science research also faces challenges in various aspects including data storage, sharing, and privacy protection, as well as how to transform massive data into reliable scientific discoveries. This paper provides a brief overview of the law of development of biological data in driving life sciences, sorts out the composition and characteristics of biological big data and its sources, as well as elaborates and discusses the common problems and challenges faced by our country under the new paradigm of data-driven life science research.
Subjects: Statistics >> Social Statistics submitted time 2024-03-27 Cooperative journals: 《中国科学院院刊》
Abstract： Since the establishment of the first human diploid cell line derived from aborted fetal tissue in the 1960s, human embryoderived cells have been widely used in biomedical field and significantly contributes to improving human health. In recent years, human pluripotent stem cells, including human embryonic stem cells (hESCs), have shown great therapeutic potential in regenerative medicine, and thus received great attention from governments and the public. However, due to various factors such as history, culture, religious beliefs, ethics and morality, research and application involving human embryo-derived cells have been controversial worldwide. This study explores the history and progress of human embryo-derived cells in the field of biomedicine, and analyzes the evolution of regulatory systems in different countries, with the aim of facilitating the improvement of China’s regulatory framework and technical requirements in this field.
Subjects: Statistics >> Social Statistics submitted time 2024-03-27 Cooperative journals: 《中国科学院院刊》
Abstract： The rapid development of biotechnology and information technology has brought life sciences into a new era of data explosion. The traditional life science research paradigm struggles to reveal the fundamental rules of complex biological systems from rapidly growing biological big data. As artificial intelligence continues to achieve disruptive breakthroughs in life science, a new paradigm driven by AI is emerging. This study delves into typical examples of life science research driven by AI, proposes the concept and key elements of the new life science research paradigm, elaborates on the cutting-edge of life science research under this new paradigm, and discusses the challenges in China.
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