摘要： Ischemia and reperfusion injury (IRI), an inevitable component in organ transplantation, contributes to inferior graft survival, compromised organ quality and limitations in organ availability. The heart is most vulnerable to IRI and tolerated ischemic times are very short. We present an entire novel heart transplant procedure during which the donor heart was continuously perfused, oxygenated at normothermia and transplanted while beating. The dynamic electrocardiogram and echocardiogram indicated an absence of ischemic injury and excellent function of the donor heart during the entire procedure. This ischemia-free beating heart transplantation (IFBHT) avoids graft IRI. The approach has thus the potential to improve transplant outcome while improving organ utilization.
摘要：The traditional serial grinding method used to investigate the internal structure of fossils cannot be readily applied to valuable fossil specimens due to its destructive and time-consuming nature. Computed tomography (CT) is an ideal non-destructive technique for investigating the internal structure of fossils, in which thousands of serial images are obtained and used to produce an accurate reconstruction of the internal morphology. This paper reviews the design, development and applications of the first CT system in China dedicated exclusively to scanning fossils. The 225 kV three-dimensional (3D) fossil micro-CT (225-3D-μCT) is capable of high-resolution volumetric imaging, with a resolution up to 5 μm, and can accommodate specimens measuring up to 100 mm in diameter and 100 mm in length. The 450 kV ordinary fossil CT (450-TY-ICT) can produce high signal-to-noise ratio (SNR) images of specimens ranging up to 800 mm in diameter and 1000 mm in length, with a resolution up to 200 μm. Two paleontological CT facilities represent a high-performance platform offering the functional diversity needed to meet the demands of studying fossils at a variety of different scales. The two machines have become indispensable for paleontological research in China.