分类: 物理学 >> 核物理学 提交时间: 2025-07-02
摘要: A novel experimental setup with spatially separated magnetic and electrostatic fields is proposed for proton and deuteron electric dipole moment (EDM) studies. The lattice design, which employs a spin compensator to achieve the “quasi-frozen” spin condition for precise measurements, demonstrates adaptability to existing facilities for high energy physics research.
分类: 物理学 >> 核物理学 提交时间: 2025-07-02
摘要: CT images provide medical practitioners with a scientific and intuitive rationale for the diagnosis of clinical diseases. The Internet of Medical Things (IoMT) and telemedicine facilitate the preservation, transmission, and application of medical data, driving the sharing of medical data, especially medical images. Encryption and decryption of CT images distributed in the IoMT and telemedicine are becoming critical because they contain a large amount of private patient-sensitive information and are vulnerable to third-party attacks, resulting in information exposure and privacy leakage . In this paper, we propose an Encryption and Decryption based Gan-attention network (EDG-Net) for CT images in the IoMT and telemedicine. EDG-Net consists of a generator, two discriminators, a domain transfer of attention, and adaptive normalization. In addition, a double encryption and decryption strategy is introduced by EDG-Net to effectively improve the security of the ciphertext image and the fidelity of the decrypted plaintext image. Specifically, during the encryption or decryption phase, the generator transforms the CT images mutually in the plaintext and ciphertext domains. Two discriminators to identify and modify the differences between these two domain transformations, especially to improve the accuracy of the reconstruction during decryption. The parameters of the trained encryption and decryption network are considered as the secret keys of encryption and decryption. Qualitative and quantitative analysis of public and private datasets demonstrates the superior performance of EDG-Net regarding encryption security and robustness, as well as decryption accuracy.
分类: 图书馆学、情报学 >> 图书馆学 提交时间: 2025-07-02
摘要: 本研究系统梳理并深度解析高校图书馆创新发展中的十个关系,旨在为“十五五”期间高校图书馆战略规划编制与创新发展提供理论依据与实践参考。通过全面把握国家教育发展战略、现代信息技术应用和新时代我国图书馆建设最新理论与实践成果,聚焦高校图书馆发展中存在的当下与战略、资源与服务、到馆与嵌入、馆员与用户、图书馆与学校、技术与人文、职业与事业、研究与业务、单馆与合作、馆长与团队十个关系展开系统性讨论和分析,进而明晰高校图书馆创新发展方向和路径。高校图书馆在“十五五”以及未来的发展中应坚持守正创新,以服务创新为根本,统筹兼顾资源建设、用户服务、技术运用、馆员培养、学术研究等各方面工作,实现高校图书馆的高质量创新发展。
分类: 其他 提交时间: 2025-07-02
摘要: 铜-67(⁶⁷Cu)凭借其适配抗体药代动力学的物理半衰期(T₁/₂=61.83 h)、中等射程β⁻粒子(Eβ⁻ₘₐₓ=577 keV,Rₘₐₓ≈2 mm)及伴随γ射线(184.6 keV)的诊疗一体化特性,在血液肿瘤靶向放射治疗中展现出显著优势。其β⁻粒子可精准杀伤微小转移灶并克服抗原异质性,同步SPECT显像能力保障了生物分布验证与剂量监测。关键技术突破驱动临床转化:光核反应⁶⁸Zn(γ,p)⁶⁷Cu实现高比活度生产(>1850 GBq/mg),双环螯合剂CB-TE2A(logK=27.9)显著降低肝脱靶风险;相较于⁹⁰Y,⁶⁷Cu的辐射剂量学优化使肿瘤/骨髓剂量比提升3.5倍,预靶向策略进一步增至4.1倍。临床研究中,⁶⁷Cu-lintuzumab治疗复发/难治性AML的客观缓解率达41%(NCT04222464),双靶点策略在抗原逃逸型ALL中实现35% MRD阴性完全缓解。未来需突破肾脏剂量限制、建立⁶⁴Cu-PET个体化剂量模型,并通过联合免疫疗法拓展应用前景。
分类: 心理学 >> 管理心理学 提交时间: 2025-07-01
摘要: 本研究挑战“生育与女性工作动力相矛盾”的社会成见,提出父母身份增益理论。研究提出父母身份认同能成为职场母亲工作动机的重要来源。这种增益通过两种机制发挥作用:父母榜样动机(母亲努力工作以成为子女榜样)和从子女探索精神中获取感染(激发工作好奇心与内在动机)。研究从个人、组织和家庭三个角度提出父母增益理论的适用情境,深化了对生育相关身份与女性工作动力关系的理解,并为提振育龄女性工作动力提出管理对策建议。
分类: 核科学技术 >> 辐射物理与技术 提交时间: 2025-07-01
摘要: The vapor diffusion and transport resulting from steam generator tube rupture (SGTR) accidents are a majorconcern threatening lead-based reactor core safety. In this study, a high-parameter SGTR experimental platformand the multiphase multi-physics processes numerical simulation were developed to investigate the phasebehavior and interaction mechanisms. This study revealed the interaction mechanisms of lead–bismuth liquidmetal and water driven by flash vaporization, jet direct contact boiling, and film boiling. The migration andevolution of the discrete phases (vapor–water mixture) were inferred from the temperature transient laws anda numerical simulation. The results revealed that the evolution of the discrete phases consists of three stages:cavity formation, flanking diffusion, and stable up-floating. The jet pressure significantly extended the disturbanceperiod. Variations in the water temperature mainly affected the decompression boiling process, alteringthe diffusion region of the discrete phases. The temperature of the liquid metal and the duration of the jet had aminimal impact on the behavior of the discrete phases. This study provides a crucial reference for constructinga complete picture of accident evolution.
分类: 核科学技术 >> 核科学与技术 提交时间: 2025-07-01
摘要: DAYU3D is a modern three-dimensional (3D) computer code for thermal-hydraulic design and accident analysis in high temperature gas-cooled reactors (HTGRs), developed by the Institute of Nuclear and New Energy Technology (INET) at Tsinghua University. Compared to the traditional codes like TINTE, the DAYU3D code has advantages due to its refined framework, improved models and more efficient algorithms. It is able to simulate the continuous movement of control rods, and is more rigorous in treating radiation heat transfer and break mass flow. Advanced computational methods significantly improve the computational efficiency of DAYU3D, achieving a time reduction of over 60% compared to TINTE. Extensive verification and validation with more than 100 cases demonstrate that DAYU3D is promising for HTGR 3D thermal-hydraulic design and accident analysis.
分类: 物理学 >> 核物理学 提交时间: 2025-06-30
摘要: A new multi-detector array named HALIMA (Hybrid Array for LIfetime MeAsurement) has been developed at Lanzhou, for nuclear structure studies in fission. The array comprises eight BGO-shielded High-Purity Germanium (HPGe) detectors and twenty fast Ce-doped Lanthanum Bromide [LaBr3(Ce)] detectors shielded with CsI(Tl). HALIMA is further complemented by two ancillary detector systems: fission fragment (FF) detectors and β detectors. This configuration enables precise sub-nanosecond lifetime measurements using a four-fold FF/β-Ge-LaBr3(Ce)-LaBr3(Ce) coincidence technique. The performance and specifications of the detectors, associated electronics, and data acquisition system are presented in detail. The advantage of FF selectivity is emphasized, which significantly enhances the sensitivity to specific fission channels. Using this approach, lifetimes of nuclear excited states populated in the spontaneous fission of 252Cf have been measured, showing good agreement with established literature values.
分类: 物理学 >> 核物理学 提交时间: 2025-06-30
摘要: The full configuration interaction quantum Monte Carlo (FCIQMC) method, originally developed in quantum chemistry, has also been successful in both molecular and condensed matter systems. Another natural extension of this methodology would be its application to nuclear structure calculations. We have developed the FCIQMC approach for studying nuclear systems. To validate the method, we applied FCIQMC to a small model space where standard shell model remain computationally feasible. Specifically, we performed calculations for Fe isotopes using pf-shell GXPF1A interaction and compared the results with those obtained from standard shell model calculations. To further demonstrate the capabilities of FCIQMC, we investigated its performance in systems exhibiting strong correlations, where conventional nuclear structure models are less effective. Using an artificially constructed strongly correlated system with a modified GXPF1A interaction, our calculations revealed that FCIQMC delivers superior results compared to many existing methods. Finally, we apply FCIQMC to Mg isotopes in the sdpf-shell model space, showing its potential to perform accurate calculations in large model spaces that are inaccessible to the shell model due to the limitations of current computational resources.
分类: 核科学技术 >> 核科学与技术 提交时间: 2025-06-30
摘要: Exploring the limits of neutron binding in atomic nuclei remains a central focus of nuclear physics. However, the experimental determination of the neutron drip line is challenging because of the minuscule production cross sections of the most neutron-rich isotopes. We investigated the effectiveness of multi-step fragmentation for producing extremely neutron-rich nuclides at relativistic energies. We demonstrate that multi-step fragmentation dominates over single-step fragmentation in thick target experiments and can enhance the yields of drip line nuclei by several orders of magnitude in a realistic experiment using fragment separators. Such enhancements open new possibilities for locating drip lines above sodium, and thus significantly expand the research horizon.
分类: 心理学 >> 发展心理学 提交时间: 2025-06-30
摘要: 在构建生育友好型社会的背景下,家庭幸福与科学育儿日益受到关注。本研究基于中国370位学龄初期儿童母亲5日的密集追踪数据,采用动态结构方程模型探讨母亲生活满意度与儿童学习行为之间的双向关系。结果发现,家庭内层面,母亲生活满意度与儿童的学习专注度、自主性、课外学习类型和学习时长均呈显著双向滞后效应;家庭间层面,仅学习自主性与母亲生活满意度呈正相关。研究揭示了母子互动的动态机制,为家庭教育实践提供理论支持。
分类: 物理学 >> 核物理学 提交时间: 2025-06-30
摘要: The tensor force changes the nuclear shell structure, and thus may result in underlying influence the collectivity and decay properties of the nucleus. We carefully examined the impact of the monopole and multipole effects originating from the tensor force on both the collectivity and the matrix element for the neutrinoless double-β (0νββ) decay, using the generator-coordinate method with an effective interaction. To analyze the effect of the tensor force, we employed an effective Hamiltonian associated with the monopole-based universal interaction that explicitly consists of the central, tensor, and spin-orbit coupling terms. The interferences among the shell structure, quadrupole collectivity, nucleon occupancy, and 0νββ matrix elements were analyzed in detail. A better understanding of the tensor force would be of great importance in reducing the theoretical uncertainty in 0νββ nuclear matrix element calculations.
分类: 物理学 >> 核物理学 提交时间: 2025-06-30
摘要: The molten salt reactor, one of the six fourth-generation reactors, utilizes liquid nuclear fuel and graphite as a moderator. Graphite also functions as a core component, forming fuel salt channels akin to a honeycomb structure. To ensure effective core design management and nuclear safety supervision, it is imperative to analyze the intricate relationship between the graphite structure of the core, fuel salt channels, and critical mass. This study employs software simulation calculations to analyze the impact of varying graphite flow channel quantities and core sizes on the reactivity of the molten salt reactor, through modeling its core dimensions and graphite flow channels. The findings reveal that the design dimensions of the graphite core correlate closely with the total uranium mass within the reaction zone. Notably, the critical total uranium mass required decreases gradually with an increase in the number of fuel salt channels, ultimately reaching a plateau followed by a slight decrease. Drawing upon the characteristics of the graphite flow channels' influence on reactor reactivity, we summarize the regulatory requirements for graphite components from a legal perspective. Furthermore, we offer recommendations for enhancing manufacturing and installation quality, preventing accidental criticality events, and closely monitoring safety parameters from a regulatory standpoint. The conclusion has been reached that there exists an optimal design value for the number of flow channels in the graphite components of liquid fuel molten salt reactors in terms of reactivity.
分类: 图书馆学、情报学 >> 图书馆学 提交时间: 2025-06-30
摘要: 【目的]高校图书馆数智化转型是贯彻落实国家数字化教育转型战略、推动高校图书馆高质量服务的必由之路。文献资源建设作为核心业务,受内外复杂要素制约,急需开展结合数据的实证研究。[方法]本文以江苏省高校图书馆7年文献资源建设相关数据,系统剖析数智化转型带来的积极变化及面临的风险挑战。[结论]针对性提出强化数智化战略思维、优化协同管理架构、数智赋能资源建设场景、构建省域特色建设模式及培育开放协作的数智生态等对策建议。
分类: 核科学技术 >> 核科学与技术 提交时间: 2025-06-29
摘要: The neutron excess effect, originating from the vanishing of one part of \(\bm{\tau}_\text{1} \cdot \bm{\tau}_\text{2}\) operator matrix elements, was appropriately considered within the Skyrme-type $\Lambda N N$ three-body interactions and applied to the deformed SHF model. Analysis of a broad range of hypernuclei, from light to heavy masses, shows that the neutron excess effect significantly improves the description of $\Lambda$ binding energies. The underlying mechanism involves reducing the $\Lambda N N$ three-body repulsive interaction by subtracting the neutron excess term, thereby improving the binding energy of the hypernucleus. In addition, the impact of this effect on the $\Lambda$ single-particle potential and the hyperon density distribution is discussed.
分类: 心理学 >> 医学心理学 分类: 心理学 >> 生理心理学 提交时间: 2025-06-28
摘要: [目的] 探索基于愤怒对抗的执行意向(II)能否减少恐惧相关障碍患者的恐惧重建和回避行为。[方法] 采用辨别性恐惧条件化范式,II组在消退前形成基于愤怒对抗的II(“如果我看到鱼类和鸟类图片感到害怕的话, 我就会觉得自己很愚蠢, 竟然会害怕一张动物图片, 我会攥紧拳头对自己感到很生气, 很生气!!”),对照组无II。测量消退期/重建期的主观指标(恐惧、愤怒、威胁预期、回避距离)和皮肤电反应。[结果] II组在消退后期对CS+的回避距离显著短于对照组;重建期恐惧、愤怒、威胁预期和回避距离均显著更低。皮肤电无组间差异。[局限] 性别比例不平衡,皮肤电指标无法区分愤怒和恐惧。[结论] 消退前形成的愤怒对抗II需多次实践后才能自动化减少恐惧重建和回避倾向。
分类: 图书馆学、情报学 >> 图书馆学 提交时间: 2025-06-28
摘要: 面向“十五五”及未来发展,公共图书馆应结合国家战略需求和自身属性特点,重点解决三个方面的问题:持续强化图书馆的基础业务建设,进一步重视图书馆创新发展设计,不断加强图书馆员能力培养,从而实现公共图书馆“十五五”及未来的高质量发展。
分类: 物理学 >> 核物理学 提交时间: 2025-06-27
摘要: Using Kolmogorov-Arnold Networks (KANs), we construct a holographic model informed by lattice QCD data. This neural network approach enables the derivation of an analytical solution for the deformation factor $w(r)$ and the determination of a constant $g$ related to the string tension. Within the KANs-based holographic framework, we further analyze heavy quark potentials under finite temperature and chemical potential conditions. Additionally, we calculate the drag force, jet quenching parameter, and diffusion coefficient of heavy quarks in this paper. Our findings demonstrate qualitative consistency with both experimental measurements and established phenomenological model.
分类: 医学、药学 >> 临床医学 提交时间: 2025-06-27 合作期刊: 《中国全科医学》
摘要: 背景 心力衰竭(HF)是严重危害全球健康的重大慢性疾病,冠心病(CHD)是心力衰竭最常见的病因,针对冠心病并发心力衰竭的危险因素构建风险预测模型,有助于医务人员对心力衰竭高危人群进行早期识别和干预。目的 系统评价我国冠心病患者并发心力衰竭风险预测模型,为相关风险预测模型的构建、选择与推广提供参考。方法 检索中国知网(CNKI)、维普网(VIP)、万方数据库知识服务平台(Wanfang Data)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、Web of Science、Embase数据库与我国冠心病患者并发心力衰竭风险预测模型相关的研究,检索时限为建库至2024年10月。由2名研究者独立筛选文献并提取信息,使用预测模型偏倚风险评价工具(PROBAST)评估纳入研究的偏倚风险及适用性。结果 共纳入27篇文献,报告了64个风险预测模型的开发情况,模型的受试者工作特征(ROC)曲线下面积(AUC)为0.511~0.989,其中63个模型AUC>0.7,提示模型整体预测性能较好;偏倚风险评估工具评估结果显示,纳入的27篇文献均为高偏倚风险,适用性偏低。年龄、左心室射血分数、糖尿病病史、高血压病史、NT-proBNP(N末端B型钠尿肽前体)、Gensini评分是模型中纳入的重要预测因子。结论 当前我国冠心病患者并发心力衰竭风险预测模型的稳定性和外推性有待进一步前瞻性、大样本研究验证,后续建模应当严格遵循PROBAST指南设计实施研究,以开发可推广性强的高质量预测模型。
分类: 医学、药学 >> 临床医学 提交时间: 2025-06-27 合作期刊: 《中国全科医学》
摘要: 背景 目前癌症治疗发生了巨大的变革,许多癌症患者以一种慢性病的模式长期生存。研究显示,众多癌症幸存者死于非肿瘤因素,而心血管疾病(CVD)则是主要原因之一。然而癌症治疗潜在的CVD常被忽视,进而导致早期干预与保护不足。估算的脉搏波传导速度(ePWV)可以反应动脉僵硬度的程度,是心血管事件的独立预测指标,其简单的计算方法为癌症患者的心血管风险分层提供了可行性。目的 通过队列研究分析ePWV与癌症患者全因死亡和心血管疾病死亡的关系。方法 本研究为回顾性队列研究,选取1999—2018年国家健康和营养检查调查(NHANES)数据库中的4 632例癌症患者为研究对象。收集患者基线资料,包括年龄、性别、种族,体质指数、胸围、基础心率、总胆固醇、高密度脂蛋白胆固醇、收缩压、舒张压、糖尿病疾病史、心血管疾病史、吸烟、饮酒状态,随访至2023年7月,记录患者全因死亡率和心血管疾病死亡率。根据动脉僵硬度协作组推导公式计算ePWV值,并根据ePWV数值大小将患者分为Q1~Q4组;比较4组患者基线水平,绘制患者全因死亡和心血管疾病死亡相关Kaplan-Meier生存曲线;采用多因素Cox比例风险模型分析患者全因死亡和心血管病死亡影响因素;绘制ePWV预测癌症心血管疾病死亡的受试者工作特征(ROC)曲线,计算ROC曲线下面积(AUC);结果 共纳入4 632例患者,平均年龄为(60.7±1.01)岁,女性2 426例(52.37%),男性2 206例(47.63%)。Q1~Q4组各1 158例(25.0%)。4组年龄、性别、种族、BMI、胸围、RHR、TC、HDL-C、SBP、DBP、糖尿病病史、心血管病史、吸烟、饮酒状态比较,差异均有统计学意义(P<0.05)。随访11.8年,4 632例癌症患者中全因死亡者830例,全因死亡发生率为17.9%;心血管疾病相关死亡376例,心血管疾病相关死亡发生率为8.1%。4组组患者全因死亡率和心血管疾病死亡率比较,差异均有统计学意义(P<0.001)。Kaplan-Meier生存分析结果显示,四组患者全因死亡和心血管疾病死亡相关生存曲线比较,差异均有统计学意义(χ2=587.11,P<0.001;χ2=322.97,P<0.001)。多因素Cox回归分析结果显示,相比于Q1组,Q2、Q3、Q4组患者发生全因死亡的危险增加(Q2:HR=1.30,95%CI=1.23~1.38,P=0.045;Q3:HR=1.46,95%CI=1.01~2.13,P=0.047;Q4:HR=1.24,95%CI=1.04~1.49,P=0.017);Q3、Q4组患者发生心血管疾病死亡的危险增加(Q3:HR=1.28,95%CI=1.05~1.56,P=0.013;Q4:HR=2.73,95%CI=1.67~4.48,P=0.026)。ROC曲线显示,Q1、Q2、Q3和Q4组对应的AUC值分别为0.514、0.624、0.598、0.772。结论 首次在癌症患者中验证了ePWV升高与全因死亡风险和心血管疾病死亡风险呈正相关。ePWV或可成为预测癌症患者死亡风险的预测因子。