钩毛茜草蒽醌类化学成分的研究 postprint

Abstract: To study the chemical constituents of China endemic plant Rubia oncotricha, the compounds were isolated and purified by silica gel, ODS, Sephadex LH-20, and their structures were elucidated by modern spectroscopic techniques. Fifteen anthraquinone compounds were isolated and identified from Rubia oncotricha, they are 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-(6'-O-acetyl)-α-rhamnosyl(1→2)-β-glucoside (1), 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl(1→2)-β-glucoside (2), 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-(3'-O-acetyl)-α-rhamnosyl (1→2)-β-glucoside (3), 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-β-glucoside (4), 1,3,6-trihydroxy-2-hydroxymethyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-β-D-glucopyranoside (5), 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-(6'-O-acetyl)-β-D-glucopyranoside (6), physcion-8-O-β-D-glucopyranoside (7), emodin-8-O-β-D-glucopyranoside (8), digiferruginol-11-O-β-gentiobioside (9), 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-(6'-O-acetyl)-β-D-xylopyranosyl-(1→2)-β-Dglucopyranoside (10), 6-hydroxyrubiadin (11), 1,2-dihydroxyanthraquinone (12), chrysophanol (13), 6-hydroxyxanthopurpurin (14), 1,3-dihydroxyanthraquinone (15). Compounds 7, 8, 14 are isolated from the genus of Rubia for the first time, compound 1~6, 9, 10, 12, 13 are isolated from Rubia oncotricha for the first time.