南丹参三萜类化学成分的研究 postprint

Abstract: To study triterpenoids from the roots of Salvia bowleyana, the 95% ethanol extract was isolated and purified by means of various column chromatographic techniques, including macroporous resin D101, MCI, normal-phase silica column, ODS, and reversed-phase HPLC. Nine compounds were obtained, and their structures were elucidated using physicochemical properties and spectroscopic data as oleanolic acid (1), 2α,3α-dihydroxyolean-12-en-28-oic acid (2), ursolic acid (3), 2α,3α-dihydroxyurs-12-en-28-oic acid (4), 2α,3β-dihydroxyurs-12-en-28-oic acid (5), 2α,3β,19α-trihydroxyurs-12-en-28-oic acid (6), 2α,3β,24-trihydroxyurs-12-en-28-oic acid (7), psiguanin A (8), and n-hexadecane acid (9). Compounds 1-9 were isolated from this plant for the first time.