Current Location:home > Browse

1. chinaXiv:202002.00012 [pdf]

Horizontal but not vertical saccades enhance memory retrieval: a meta-analysis and systematic review

Qin, Xiao-jing; Yang, Han-xue ; Cui, Ji-fang ; Ye, Jun-yan ; Wang, Ya
Subjects: Psychology >> Cognitive Psychology

BACKGROUND: Saccade-induced retrieval enhancement (SIRE) refers to the phenomenon that active engaging of horizontal eye movements before recall would enhance subsequent memory performance. This effect is generally thought to be the result of interhemispheric interaction stimulated by saccades. Nonetheless, recent findings do not fully support this hypothesis. An alternative explanation is that saccades promote memory retrieval by improving top-down attention control. Thus, the mechanisms of SIRE are unclear, the present meta-analysis quantitatively analyzed the effect of saccades on memory performance and examined the mechanisms of SIRE through moderator analysis. METHODS: We searched "Web of Science", "PubMed", and "Springer" for peer reviewed papers using the keywords "eye movements + memory" and "saccades + memory". Twenty-two papers were included in the final analysis. RESULTS: There was a significant facilitation of horizontal saccades on overall memory performance, with a pooled effect size (Cohen’s d) of 0.45 (p < 0.001). However, the overall effect of vertical saccades was not significant (d = 0.1, p = 0.14). Moderation analysis showed that the handedness of participants was a significant moderator of the SIRE, with strongly right-handed individuals benefited more from horizontal saccades than non-strongly right-handed individuals (p < 0.01). CONCLUSION: Horizontal saccades improved memory performances, particularly for the strongly right-handed individuals, these results support the interhemispheric interaction hypothesis.

submitted time 2020-02-05 Hits7931Downloads346 Comment 0

2. chinaXiv:202002.00010 [pdf]

A Meta-Analysis of Mental Time Travel Impairments in Autism Spectrum Disorders

Jun-yan Ye; Xiao-jing Qin; Ji-fang Cui; Lu-xia Jia; Ya Wang; Christos Pantelis; Raymond CK Chan
Subjects: Psychology >> Medical Psychology

Individuals with autism spectrum disorders (ASD) have a wide range of cognitive impairments. Mental time travel (MTT) is the ability to mentally re-experience past events and pre-experience possible future events. Studies have shown MTT impairments in individuals with ASD, however, these findings may be confounded by a number of factors including verbal ability to report MTT, factors related to MTT task and demographic factors of participants. The present study provided a meta-analysis on MTT deficits in individuals with ASD and examined the potential moderating variables for these impairments. Twenty-six studies were included, and the participants comprised 667 individuals with ASD and 671 healthy controls. Results showed significant overall MTT impairments (Cohen’s d = ?0.95) in individuals with ASD. Moderator and meta-regression analyses revealed that verbal IQ was significantly related to MTT impairments; type of MTT, type of task, measurement indices of MTT, age of participants, gender ratio and full IQ did not explain the MTT impairments. These findings suggest that MTT is severely impaired in individuals with ASD, verbal IQ contributed to MTT impairments, and task characteristics did not affect the degree of impairments.

submitted time 2019-11-05 Hits7831Downloads297 Comment 0

3. chinaXiv:201909.00192 [pdf]

CAN4Age: Chinese affective norms for 4-character words rated by older and younger adults

Liu, Pingping; Lu, Qin; Zhang, Zhen; Han, Buxin
Subjects: Psychology >> Applied Psychology

Age-related differences in affective meanings of words are widely used by researchers studying emotions, word recognition, attention, memory and text -based sentiment analysis. However, no Chinese affective norms for older adults are available. This article firstly presents the available large-scale Chinese affective norms for 2, 061 4-character words rated in labs by 114 older and 150 younger adults (CAN4Age) who evaluated these words on four dimensions: valence, arousal, dominance, and familiarity. We also compiled 4 lexical variables for each word, including word frequency, word complexity, character frequency and character complexity. In general, older adults tend to evaluate emotional words more extremely than younger adults do. That is, they rate positive words as more positive and negative words as more negative than younger adults do. Specifically, older adults tend to perceive positive words as more arousing and less controllable and negative words as less arousing and more controllable than that of younger adults. This age-related database will enable researchers to study how emotional characteristics of words influence their cognitive processing, and how this influence evolves with age in Chinese. This age-related difference study on affective norms not only provides insights to cognitive neuroscience, gerontology and psychology in experimental studies, but the produced affective word collection also has great value as a resource for affective analysis in natural language processing applications. These norms can be downloaded as supplemental materials with this published article.

submitted time 2019-09-18 Hits9656Downloads391 Comment 0

4. chinaXiv:201703.01054 [pdf]

Impaired spinal glucocorticoid receptor signaling contributes to the attenuating effect of depression on mechanical allodynia and thermal hyperalgesia in rats with neuropathic pain

Wei, Xiao; Sun, Yuqi; Luo, Fei
Subjects: Biology >> Neurobiology

Although depression-induced altered pain perception has been described in several laboratory and clinical studies, its neurobiological mechanism in the central nervous system, particularly in the spinal dorsal horn remains unclear. In this study, we therefore aimed to clarify whether nociceptive sensitivity of neuropathic pain is altered in the olfactory bulbectomy (OB) model of depression and whether glucocorticoid receptor (GR), which is involved in the etio-pathologic mechanisms of both major depression and neuropathic pain, contributes to these processes in the spinal dorsal horn of male Sprague-Dawley rats. The results showed that mechanical allodynia and thermal hyperalgesia induced by spinal nerve ligation (SNL) were attenuated in OB-SNL rats with decreased spinal GR expression and nuclear translocation, while NOB (non-olfactory bulbectomy)-SNL rats showed an increased spinal GR nuclear translocation. Decreased GR nuclear translocation with normal mechanical nociception and hypoalgesia of thermal nociception were observed in OB-Sham rats, too. Intrathecal injection of GR agonist dexamethasone (4 ?g / rat / day for 1 week) eliminated the attenuating effect of depression on the nociceptive hypersensitivity in OB-SNL rats and aggravated neuropathic pain in NOB-SNL rats, associating with the up-regulation of BDNF, TrkB and NR2B expression in the spinal dorsal horn. The present study shows that depression attenuates the mechanical allodynia and thermal hyperalgesia of neuropathic pain and suggests that altered spinal GR-BDNF-TrkB signaling may be one of the reasons for depression-induced hypoalgesia.

submitted time 2017-07-24 Hits2778Downloads1121 Comment 0

5. chinaXiv:201703.01054 [pdf]

Impaired spinal glucocorticoid receptor signaling contributes to the attenuating effect of depression on mechanical allodynia and thermal hyperalgesia in rats with neuropathic pain

Wei, Xiao; Sun, Yuqi; Luo, Fei
Subjects: Biology >> Neurobiology

Although depression-induced altered pain perception has been described in several laboratory and clinical studies, its neurobiological mechanism in the central nervous system, particularly in the spinal dorsal horn remains unclear. In this study, we therefore aimed to clarify whether nociceptive sensitivity of neuropathic pain is altered in the olfactory bulbectomy (OB) model of depression and whether glucocorticoid receptor (GR), which is involved in the etio-pathologic mechanisms of both major depression and neuropathic pain, contributes to these processes in the spinal dorsal horn of male Sprague-Dawley rats. The results showed that mechanical allodynia and thermal hyperalgesia induced by spinal nerve ligation (SNL) were attenuated in OB-SNL rats with decreased spinal GR expression and nuclear translocation, while NOB (non-olfactory bulbectomy)-SNL rats showed an increased spinal GR nuclear translocation. Decreased GR nuclear translocation with normal mechanical nociception and hypoalgesia of thermal nociception were observed in OB-Sham rats, too. Intrathecal injection of GR agonist dexamethasone (4 ?g / rat / day for 1 week) eliminated the attenuating effect of depression on the nociceptive hypersensitivity in OB-SNL rats and aggravated neuropathic pain in NOB-SNL rats, associating with the up-regulation of BDNF, TrkB and NR2B expression in the spinal dorsal horn. The present study shows that depression attenuates the mechanical allodynia and thermal hyperalgesia of neuropathic pain and suggests that altered spinal GR-BDNF-TrkB signaling may be one of the reasons for depression-induced hypoalgesia.

submitted time 2017-03-31 Hits2571Downloads919 Comment 0

  [1 Pages/ 5 Totals]