Current Location:home > Browse

1. chinaXiv:201905.00002 [pdf]

Females Meditate and Males Play Games: Gender Differences in the Benefits of Meditation Training

Wang, Yuzheng; Chen, Yahong; Sun, Yuqi; Zhang, Ke; Wang, Ning; Sun, Yabin; Lin, Xiaoxiao; Wang, Jinyan; Luo, Fei
Subjects: Psychology >> Applied Psychology

Although extensive research has shown the benefits of meditation on attention, evidence for the benefits of short-term meditation training remains scarce. In addition, prior studies on these benefits have included considerably more females than males, potentially concealing gender differences in attention training effects. Here we present a longitudinal study including equal-sample male and female participants to explore potential gender differences in short-term meditation training effects on an attentional blink (AB) task. One hundred and sixty-five college students were randomly divided into three groups: meditation training, video game training and control (no training). Participants were asked to complete the Five-Facet Mindfulness Questionnaire and the State-Trait Anxiety Inventory, and to rate their level of emotional state and time spent on video game playing per day. Participants then completed a 4-day, 20-min training including meditation training, video game training, or a waiting period (control). After training, participants rated their arousal state and emotional state, and performed the AB task. Results showed that participants who completed either short-term meditation training or video game training showed significant improvement on AB performance. Interestingly, meditation training was more effective in females, while video game training was more effective in males. Meditation training, but not video game training, decreased anxiety scores. The current results indicate that gender plays an important role in the benefits of attention training. It is essential that clinicians take gender into consideration when implementing meditation based therapy.

submitted time 2019-05-05 Hits1362Downloads218 Comment 0

2. chinaXiv:201605.01248 [pdf]

The Metabolic Regulator Histone Deacetylase 9 Contributes to Glucose Homeostasis Abnormality Induced by Hepatitis C Virus Infection

Chen, Jizheng; Guo, Min; Tang, Hong; Chen, Xinwen; Wang, Ning; Dong, Mei; Li, Zhong; Han, Xiao; Wang, Qian; Zhao, Yang; Zhuo, Zhiyong; Zhang, Chao; Chi, Xiumei; Pan, Yu; Jiang, Jing; Niu, Junqi; Yang, Dongliang
Subjects: Biology >> Biophysics

Class Ila histone deacetylases (HDACs), such as HDAC4, HDAC5, and HDAC7, provide critical mechanisms for regulating glucose homeostasis. Here we report that HDAC9, another class Ila HDAC, regulates hepatic gluconeogenesis via deacetylation of a Forkhead box 0 (FoxO) family transcription factor, FoxO1, together with HDAC3. Specifically, HDAC9 expression can be strongly induced upon hepatitis C virus (HCV) infection. HCV-induced HDAC9 upregulation enhances gluconeogenesis by promoting the expression of gluconeogenic genes, including phosphoenolpyruvate carboxykinase and glucose-6-phosphatase, indicating a major role for HDAC9 in the development of HCV-associated exaggerated gluconeogenic responses. Moreover, HDAC9 expression levels and gluconeogenic activities were elevated in livers from HCV-infected patients and persistent HCV-infected mice, emphasizing the clinical relevance of these results. Our results suggest HDAC9 is involved in glucose metabolism, HCV-induced abnormal glucose homeostasis, and type 2 diabetes.

submitted time 2016-05-11 Hits267Downloads169 Comment 0

  [1 Pages/ 2 Totals]